6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid CAS 77140-86-4

Purity 97%+In StockPharmaceutical Standards
CAS No.77140-86-4
Molecular FormulaC11H13NO3
Molecular Weight207.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid CAS 77140-86-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 207.23 g/mol gives 6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (CAS 77140-86-4) is a high-purity analytical reference standard with the molecular formula C11H13NO3 and a molecular weight of 207.23 g/mol.

6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid (C11H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H13NO3
Molecular Weight207.23 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms1

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