6-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid CAS 77140-90-0
| CAS No. | 77140-90-0 |
| Molecular Formula | C11H13NO2 |
| Molecular Weight | 191.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 77140-90-0) is a high-purity analytical reference standard with the molecular formula C11H13NO2 and a molecular weight of 191.23 g/mol.
The molecular framework of 6-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (C11H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13NO2 |
| Molecular Weight | 191.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate (CAS 1028330-54-2)
- 2-Methyl-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid (CAS 1038549-53-9)
- 1,2,3,4-Tetrahydroisoquinoline-1-acetic Acid (CAS 105400-81-5)
- 6-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260637-29-3)
- 7-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260639-77-7)
- 4-Methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1367666-46-3)
- 5-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 151637-59-1)
- Methyl 1,2,3,4-tetrahydroisoquinoline-6-carboxylate (CAS 185057-00-5)
Recommended Standards
- 6-Methoxy-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one (CAS 72503-43-6)
- 6-Methyl-1,2,3,4-tetrahydroquinoline-8-carboxylic acid (CAS 856086-70-9)
- 6-Methoxy-3,4-dihydronaphthalen-1(2H)-one oxime (CAS 54951-36-9)
- 6-p-Tolyl-morpholin-3-one (CAS 951627-10-4)
- 2-Amino-N-(2-methoxyethyl)-3-phenylpropanamide hydrochloride (CAS 1236255-09-6)
- 1,2,4,5-Tetraethynylbenzene (CAS 70603-31-5)
- 4-Bromo-6-fluoro-1-benzofuran (CAS 325487-80-7)
- [(4-chlorophenyl)methyl][2-(diethylamino)ethyl]amine (CAS 84434-83-3)
- 6-Chloro-3-(difluoromethyl)-2-fluoropyridin-4-amine (CAS 1805325-09-0)
- 3-(6-Methyl-quinazolin-4-ylamino)-propionic acidhydrochloride (CAS 435345-11-2)
- 2-Amino-N-((1-benzylpiperidin-2-yl)methyl)-N-methylacetamide (CAS 1353984-47-0)
- 1-(4-(((tert-Butyldimethylsilyl)oxy)methyl)phenyl)ethan-1-one (CAS 93131-87-4)
- 2-Chloro-N-(2-(ethyl(m-tolyl)amino)ethyl)acetamide (CAS 42992-30-3)
- Peptide WE-14 (CAS 115136-18-0)
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