2,5-Difluorobenzene-1-thiol CAS 77380-28-0
| CAS No. | 77380-28-0 |
| Molecular Formula | C6H4F2S |
| Molecular Weight | 146.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-Difluorobenzene-1-thiol is closely related to sulfur-containing functionality, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,5-Difluorobenzene-1-thiol (CAS 77380-28-0), molecular formula C6H4F2S and molecular weight 146.16 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,5-Difluorobenzene-1-thiol (C6H4F2S) contains sulfur-containing functionality, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 146.16 g/mol, it falls into the low-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,5-Difluorobenzene-1-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4F2S |
| Molecular Weight | 146.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluorobenzene Standards
- 2,3-Difluorobenzene-1-thiol (CAS 130922-39-3)
- 4,5-Difluorobenzene-1,2-diol (CAS 147300-08-1)
- 3,5-Difluorobenzene-1,2-diol (CAS 147300-09-2)
- 2,4-Difluorobenzene-1,3-diol, 97% (CAS 195136-71-1)
- 2,5-Difluorobenzene-1,4-diol (CAS 367-35-1)
- 2,6-Difluorobenzene-1,4-diol (CAS 84959-65-9)
- 3,6-Difluorobenzene-1,2-diol (CAS 75626-23-2)
- 2,6-Difluorobenzene-1,4-diamine (CAS 3743-86-0)
Recommended Standards
- 1-But-3-En-1-Ynyl-4-Fluoro-Benzene (CAS 214552-85-9)
- 2-Fluoro-1-(piperazin-1-yl)ethanone (CAS 6442-83-7)
- 1-(4-fluoro-2-methyl-pyrazol-3-yl)ethanone (CAS 2303288-46-0)
- 2-Oxothiolane-3-carboxylic acid (CAS 222046-78-8)
- (2S)-2-Amino-1-(3-((dimethylamino)methyl)piperidin-1-yl)-3-methylbutan-1-one (CAS 1354027-27-2)
- 6,7-Dimethoxycinnoline (CAS 17356-77-3)
- 6-(5-(1-Acetyl-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid (CAS 300816-71-1)
- Ponatinib Impurity 57 (CAS CATO-C4X-226957)
- Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate (CAS 77368-22-0)
- 5-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-indazole (CAS 1421252-94-9)
- Barium D-3-trifluoroacetylcamphorate (CAS 36539-57-8)
- Calcium Phenylpyruvate Impurity 1 (CAS 1632-49-1)
- N-(2-(methylthio)phenyl)thietan-3-amine (CAS 1865614-73-8)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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