Methoxamine Impurity 17 CAS 776-99-8
| CAS No. | 776-99-8 |
| Molecular Formula | C11H14O3 |
| Molecular Weight | 194.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Methoxamine Impurity 17 (CAS 776-99-8), a pharmacopoeial impurity reference standard (molecular formula C11H14O3, MW 194.23 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Methoxamine Impurity 17 (C11H14O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Methoxamine Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H14O3 |
| Molecular Weight | 194.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Methoxamine Standards
- Methoxamine Impurity 1 (CAS 5803-30-5)
- Methoxamine Impurity 6 (CAS 1835-04-7)
- Methoxamine Impurity 18 (CAS CATO-C4X-202218)
- Methoxamine Impurity 8 (CAS CATO-C4X-20228)
- Methoxamine Impurity 11 (CAS 54419-64-6)
- Methoxamine Impurity 10 (CAS 1201-38-3)
- Methoxamine Impurity 9 (CAS 49710-99-8)
- Methoxamine Impurity 24 (CAS CATO-C4X-202224)
Recommended Standards
- Oxybutynin Impurity 6 (CAS 76142-48-8)
- Neostigmine Impurity 25 (CAS 76418-45-6)
- Tetracaine Impurity 16 (CAS CATO-C4X-192316)
- Neostigmine impurity 34 (CAS CATO-C4X-204234)
- Tildipirosin impurity 3 (CAS CATO-C4X-32763)
- Lasmiditan Impurity 36 HBr (CAS CATO-C4X-247836)
- Donepezil Impurity 40 (CAS 923571-16-8)
- 3-(2,4,6-Trifluorophenyl)acrylic acid (CAS 239795-59-6)
- N-(4-Bromo-1-methyl-5-pyrazolyl)pivalamide (CAS 679394-11-7)
- (4-Phenylpyrrolidin-3-yl)-carbamic Acid tert-Butyl Ester (CAS 351360-61-7)
- 1',5',6',7'-Tetrahydrospiro[cyclopentane-1,4'-cyclopenta[d]pyrimidine]-2'(3'H)-thione (CAS 5778-25-6)
- Ethyl 2-ethoxy-6-methylbenzoate (CAS 134753-19-8)
- 5-Bromo-2-ethoxy-n-(3-hydroxypropyl)benzenesulfonamide (CAS 1018158-47-8)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com