Fluorometholone Acetate CAS 3801-06-7
| CAS No. | 3801-06-7 |
| Molecular Formula | C24H31FO5 |
| Molecular Weight | 418.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fluorometholone Acetate (CAS 3801-06-7), molecular formula C24H31FO5 and molecular weight 418.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Fluorometholone Acetate (C24H31FO5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Fluorometholone Acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H31FO5 |
| Molecular Weight | 418.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Fluorometholone Standards
- Fluorometholone Impurity 6 (CAS 110664-58-9)
- Fluorometholone Epoxy Analog (CAS 83873-17-0)
- Fluorometholone Impurity N12 (CAS 382-52-5)
- Fluorometholone Impurity 8 (CAS CATO-C4X-19338)
- Fluorometholone Impurity 2 (CAS 130145-14-1)
- Fluorometholone Acetate 6,9(11)-diene Impurity (CAS 95955-20-7)
- Fluorometholone Impurity 5 (CAS 378-36-9)
- Fluorometholone Impurity 11 (CAS CATO-C4X-193311)
Recommended Standards
- Idebenone Impurity 7 (CAS 319906-76-8)
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- L 659066 (CAS 114914-42-0)
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- tert-Butyl ((1S,3R)-3-amino-2,2-dimethylcyclobutyl)carbamate (CAS 1932308-17-2)
- Methyl 2-amino-2-(2-chloro-4-methoxyphenyl)acetate (CAS 1888616-97-4)
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- Ethyl 1-((2-ethoxy-2-oxoethylamino)methyl)cyclopropanecarboxylate (CAS 400841-00-1)
- 2-(Propylthio)nicotinamide (CAS 175135-26-9)
- 4-(Aminomethyl)piperidine-4-carboxylic acid hydrochloride (CAS 1205749-11-6)
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- 2,4(1H,3H)-QUINAZOLINEDIONE, 3-AMINO-1-CYCLOPROPYL-6,7-DIFLUORO-8-METHYL- (CAS 351368-44-0)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
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