Brexpiprazole Impurity 51 CAS 79145-59-8
| CAS No. | 79145-59-8 |
| Molecular Formula | C12H12ClNO2 |
| Molecular Weight | 237.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Brexpiprazole Impurity 51 (CAS 79145-59-8, C12H12ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Brexpiprazole Impurity 51 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Brexpiprazole Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClNO2 |
| Molecular Weight | 237.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Brexpiprazole Standards
- Brexpiprazole impurity 124 (CAS 146121-18-8)
- Brexpiprazole Impurity 20 (CAS 616227-75-9)
- Brexpiprazole Impurity 6 (CAS 1886188-97-1)
- Brexpiprazole Impurity 87 (CAS 62969-59-9)
- Brexpiprazole Impurity 16 (CAS 2116542-22-2)
- Brexpiprazole Impurity 161 (CAS CATO-C4X-1131161)
- Brexpiprazole Impurity 23 (CAS CATO-C4X-113123)
- Brexpiprazole Impurity 24 (CAS 2809183-06-8)
Recommended Standards
- Lornoxicam Impurity 34 (CAS 1333316-61-2)
- 697793-63-8 2-Chloro-6,7-dimethoxy-4-methylquinoline DTXSID60651052 (CAS 697793-63-8)
- 5-Chloro-2-((1-methyl-1H-pyrazol-4-yl)methoxy)aniline (CAS 1006962-56-6)
- 58868-27-2 2-chloro-5,8-dimethoxy-4-methylquinoline DTXSID80296525 (CAS 58868-27-2)
- Polmacoxib Impurity 5 (CAS 1778703-66-4)
- Upadacitinib Impurity 168 (CAS CATO-C4X-2405168)
- Tadalafil Impurity 93 (CAS CATO-C4X-108793)
- 2-((6-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-oxo-4H-pyran-3-yl)oxy)-N-phenylacetamide (CAS 898455-75-9)
- N-cyclopropyl-5-fluoropyridin-2-amine (CAS 1251244-04-8)
- (4-Fluoro-2-(1H-imidazol-1-yl)phenyl)methanamine (CAS 869591-89-9)
- 3-(Methylthio)-5-nitropyridine (CAS 1881296-22-5)
- 5-Fluoro-1H-indole-2-carbaldehyde (CAS 220943-23-7)
- 1-(Piperidin-2-yl)propan-1-ol (CAS 63401-12-7)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com