Dacomitinib Impurity 41 CAS CATO-C4X-208641

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-208641
Molecular FormulaC20H27N5O2
Molecular Weight369.46 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dacomitinib Impurity 41 CAS CATO-C4X-208641 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 369.46 g/mol gives Dacomitinib Impurity 41 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Dacomitinib Impurity 41 (CAS CATO-C4X-208641) is a certified pharmaceutical impurity reference standard with the molecular formula C20H27N5O2 and a molecular weight of 369.46 g/mol.

Based on its molecular formula C20H27N5O2, Dacomitinib Impurity 41 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 369.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Dacomitinib Impurity 41 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H27N5O2
Molecular Weight369.46 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms5

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