1-Isopropyl-3-methyl-4-nitro-1H-pyrazole-5-carboxamide CAS 792969-86-9
| CAS No. | 792969-86-9 |
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Isopropyl-3-methyl-4-nitro-1H-pyrazole-5-carboxamide (CAS 792969-86-9) is a high-purity analytical reference standard with the molecular formula C8H12N4O3 and a molecular weight of 212.21 g/mol.
The molecular framework of 1-Isopropyl-3-methyl-4-nitro-1H-pyrazole-5-carboxamide (C8H12N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12N4O3 |
| Molecular Weight | 212.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
Related Isopropyl Standards
- Isopropyl 3,4,5-trihydroxybenzoate (CAS 1138-60-9)
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- 1-Isopropyl-5-propoxy-1H-pyrazole-4-carboxylic acid (CAS 1437432-63-7)
- Isopropyl 4,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 333439-11-5)
- 6-Isopropyl-2-(methylthio)pyrimidine-4-carboxylic acid (CAS 1263207-08-4)
- Methyl 6-isopropyl-1-oxaspiro[2.5]octane-2-carboxylate (CAS 1487361-64-7)
- Methyl 2-isopropyl-5-methyl-1-oxaspiro[2.4]heptane-2-carboxylate (CAS 1559423-20-9)
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Recommended Standards
- 1-Butyl-3-nitro-1H-pyrazole-4-carboxamide (CAS 61717-02-0)
- 1-phenyl-1H,4H,5H-pyrazolo[3,4-d]pyridazin-4-one (CAS 40995-47-9)
- 1,4-Di(4H-1,2,4-triazol-4-yl)benzene (CAS 681004-60-4)
- 2-(((3-Oxo-2,3-dihydro-1H-pyrazol-4-yl)methylene)amino)benzonitrile (CAS 339020-78-9)
- 3-[(2-Bromo-4-isopropylphenoxy)methyl]pyrrolidinehydrochloride (CAS 1219964-51-8)
- 3-Fluoro-1H-pyrrolo[3,2-c]pyridine-6-carbonitrile (CAS 1352398-08-3)
- Methyl 2-(4-Chloro-3-cyanophenyl)acetate (CAS 1261572-64-8)
- 2-(2-Chloro-5-nitrophenyl)-5-methyl-1H-1,2,4-triazol-3(2H)-one (CAS 114499-57-9)
- 5-Iodo-2-methyl-3-nitrobenzoic acid (CAS 1517254-24-8)
- 3-Amino-5-(methoxycarbonyl)phenylboronic Acid (CAS 380430-56-8)
- 1-Ethyl-1H-imidazol-2-amine (CAS 22944-65-6)
- 2-(2-((1-Amino-1-oxopropan-2-yl)thio)thiazol-4-yl)acetic acid (CAS 1339344-80-7)
- 1-(2-Amino-4,5-dimethylphenyl)ethanone (CAS 106634-67-7)
- Neuropeptide Y (porcine) trifluoroacetate salt (CAS 83589-17-7)
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