Aztreonam Impurity 34 CAS 80582-09-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.80582-09-8
Molecular FormulaC4H8N2O4S
Molecular Weight180.18 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Aztreonam Impurity 34 CAS 80582-09-8 chemical structure

Description

The molecular framework of Aztreonam Impurity 34 (C4H8N2O4S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Aztreonam Impurity 34 (CAS 80582-09-8) is a certified pharmaceutical impurity reference standard with the molecular formula C4H8N2O4S and a molecular weight of 180.18 g/mol.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC4H8N2O4S
Molecular Weight180.18 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1980
Nitrogen Atoms2
Sulfur Atoms1

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