Ramelteon Impurity 62 CAS 809097-20-8
| CAS No. | 809097-20-8 |
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ramelteon Impurity 62.
As a process- or degradation-related impurity, Ramelteon Impurity 62 (CAS 809097-20-8, C16H21NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ramelteon Impurity 62 (C16H21NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Related Ramelteon Standards
- Ramelteon Metabolite M-II (CAS 896736-21-3)
- Ramelteon Impurity 31 (CAS 1204581-50-9)
- Ramelteon Impurity 36 (CAS CATO-C4X-262236)
- Ramelteon Impurity 38 (CAS 1260675-80-6)
- Ramelteon Impurity 15 (CAS 880152-61-4)
- Ramelteon Impurity 33 (CAS 2517684-01-2)
- Ramelteon Impurity 59 (CAS CATO-C4X-262259)
- Ramelteon Impurity 28 (CAS CATO-C4X-262228)
Recommended Standards
- Hyoscyamine Impurity 11 (CAS CATO-C4X-343711)
- rac 7-Hydroxy Propranolol (CAS 81907-81-5)
- Boc-D-Thr(tBu)-OH (CAS 201217-86-9)
- Boc-Thr(tBu)-OH (CAS 13734-40-2)
- Tepotinib impurity 24 (CAS CATO-C4X-337424)
- Metaraminol Impurity 18 (CAS CATO-C4X-225218)
- Vincamine EP Impurity C (CAS 32790-09-3)
- 3-Bromo-5-methoxypyridine 3-bromo-5-methoxy pyridine 3-bromo-5-methoxy-pyridine 5-bromo-3-methoxypyridine 5-bromopyridin-3-yl methyl ether 5-methoxy-3-bromopyridine 50720-12-2 (CAS 50720-12-2)
- N-(2-Fluoro-6-nitrophenyl)guanidine (CAS 1217015-88-7)
- 2-Methoxy-5-(trifluoromethoxy)benzoic acid (CAS 191604-88-3)
- (5-Chloro-6-methylpyridin-3-yl)methanol (CAS 917835-64-4)
- Phytanic acid (CAS 14721-66-5)
- Sarpogrelate Impurity 11 (CAS 138656-66-3)
- Neuropeptide FF (5-8) (CAS 152050-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com