Ramelteon Impurity 36 CAS CATO-C4X-262236
| CAS No. | CATO-C4X-262236 |
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ramelteon Impurity 36.
As a process- or degradation-related impurity, Ramelteon Impurity 36 (CAS CATO-C4X-262236, C16H21NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ramelteon Impurity 36 (C16H21NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ramelteon Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Ramelteon Standards
- Ramelteon Metabolite M-II (CAS 896736-21-3)
- Ramelteon Impurity 31 (CAS 1204581-50-9)
- Ramelteon Impurity 38 (CAS 1260675-80-6)
- Ramelteon Impurity 62 (CAS 809097-20-8)
- Ramelteon Impurity 15 (CAS 880152-61-4)
- Ramelteon Impurity 33 (CAS 2517684-01-2)
- Ramelteon Impurity 59 (CAS CATO-C4X-262259)
- Ramelteon Impurity 28 (CAS CATO-C4X-262228)
Recommended Standards
- Rolipram (CAS 61413-54-5)
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- Ixazomib Impurity 46 (CAS CATO-C4X-126746)
- Irinotecan EP Impurity A HCl Trihydrate (CAS 158406-44-1)
- Ezetimibe Impurity 138 (CAS CATO-C4X-1098138)
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- 2-Chloro-5-(difluoromethyl)-6-hydroxynicotinaldehyde (CAS 1806007-20-4)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
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