Tepotinib impurity 24 CAS CATO-C4X-337424
| CAS No. | CATO-C4X-337424 |
| Molecular Formula | C33H36N6O5 |
| Molecular Weight | 596.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tepotinib impurity 24.
As a process- or degradation-related impurity, Tepotinib impurity 24 (CAS CATO-C4X-337424, C33H36N6O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tepotinib impurity 24 (C33H36N6O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tepotinib impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C33H36N6O5 |
| Molecular Weight | 596.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tepotinib Standards
- Tepotinib impurity 1 (CAS 1103506-80-4)
- Tepotinib impurity 25 (CAS CATO-C4X-337425)
- Tepotinib impurity 6 (CAS CATO-C4X-33746)
- Tepotinib impurity 8 (CAS CATO-C4X-33748)
- Tepotinib impurity 5 (CAS 1233361-38-0)
- Tepotinib impurity 2 (CAS 1233361-36-8)
- Tepotinib impurity 15 (CAS CATO-C4X-337415)
- Tepotinib Impurity 36 (CAS 1103507-25-0)
Recommended Standards
- N-(9-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-9H-purin-6-yl)benzamide (CAS 956139-16-5)
- Benidipine Impurity 5 (CAS CATO-C4X-11205)
- 1,1,2,2-Tetrakis(4-(1H-pyrazol-3-yl)phenyl)ethene (CAS 2845187-26-8)
- Nintedanib Impurity 171 (CAS CATO-C4X-1814171)
- Osimertinib Impurity 86 (CAS CATO-C4X-204586)
- Ibrutinib Impurity 184 (CAS CATO-C4X-1064184)
- Berberine Impurity 24 (CAS 430433-40-2)
- 2-(Isopropylthio)-1,3-benzothiazol-6-amine (CAS 64350-93-2)
- 8-Methylisoquinoline-1-carbonyl chloride (CAS 174873-76-8)
- 1,7-Diazaspiro[4.4]nonane (CAS 34357-58-9)
- (4-((2-Ethyl-1H-imidazol-1-yl)methyl)piperidin-1-yl)(4-propyl-1,2,3-thiadiazol-5-yl)methanone (CAS 1334374-57-0)
- 1-(4-(4-(1-Benzylpiperidin-4-yl)piperazin-1-yl)phenyl)ethan-1-one (CAS 331978-89-3)
- 7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 869947-41-1)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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