5-Amino-2-chlorobenzothiazole CAS 80945-82-0
| CAS No. | 80945-82-0 |
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-2-chlorobenzothiazole.
CATO supplies 5-Amino-2-chlorobenzothiazole (CAS 80945-82-0), a certified reference material (molecular formula C7H5ClN2S, MW 184.65 g/mol) for analytical method development and quality control.
The molecular framework of 5-Amino-2-chlorobenzothiazole (C7H5ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClN2S |
| Molecular Weight | 184.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
- 4-Chlorobenzo[d]thiazol-7-amine (CAS 70202-02-7)
- 5-Chloro-1,3-dihydro-2H-benzo[d]imidazole-2-thione (CAS 25369-78-2)
- 4-Chlorobenzo[d]thiazol-5-amine (CAS 70202-01-6)
- 5-Chloro-1H-pyrrolo[2,3-b]pyridine-4-thiol (CAS 2415987-86-7)
- 6-phenylthiomorpholin-3-one (CAS 42109-49-9)
- N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)acetamide (CAS 126099-59-0)
- 2-Chloro-6-ethoxyisonicotinic acid (CAS 6291-10-7)
- (4R,5R)-2-chloro-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine (CAS 1236123-69-5)
- 4-Amino-5-benzoyl-2-{[(4-tert-butylphenyl)methyl]sulfanyl}thiophene-3-carbonitrile (CAS 478081-62-8)
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Why CATO?
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