3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline CAS 860785-05-3
| CAS No. | 860785-05-3 |
| Molecular Formula | C14H9ClF3N3 |
| Molecular Weight | 311.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline (CAS 860785-05-3) is a high-purity analytical reference standard with the molecular formula C14H9ClF3N3 and a molecular weight of 311.69 g/mol.
3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline (C14H9ClF3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3N3 |
| Molecular Weight | 311.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 7-Benzyl-4-chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1365627-43-5)
- 3-((2-Chloro-4-fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 1706455-65-3)
- 3-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-methyl-1H-indole (CAS 1903753-93-4)
- 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine (CAS 811432-17-4)
- Ethyl (2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)carbamate (CAS 321432-03-5)
- Methyl 1-((2-chloro-4-nitrophenoxy)methyl)-1h-pyrazole-3-carboxylate (CAS 1001499-91-7)
- 1-((2-Chloro-4-nitrophenoxy)methyl)-1h-pyrazole-3-carbohydrazide (CAS 1004194-19-7)
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Recommended Standards
- 5-(2-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-04-3)
- 5-(3-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-02-1)
- 6-(7-Chloro-1,8-naphthyridin-2-yl)-5H-pyrrolo[3,4-b]pyrazine-5,7(6H)-dione (CAS 55112-93-1)
- Clodinafop (racemic) (CAS 87135-08-8)
- 4-bromo-3,5-difluoro-pyridine (CAS 1092352-40-3)
- 1-(4-Chloro-3-fluorophenyl)-2-(3-chlorophenyl)ethan-1-one (CAS 1623432-55-2)
- 2-(Tetrahydro-2H-pyran-4-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-ol (CAS 1707568-57-7)
- Methyl 3-((2-hydroxybenzyl)amino)benzoate (CAS 1096932-09-0)
- (6-(Indolin-1-yl)-5-methylpyridin-3-yl)methanol (CAS 1355203-58-5)
- 2-chlorocyclopentan-1-amine (CAS 61888-96-8)
- N-(3-Bromobenzylidene)aniline (CAS 18467-14-6)
- (4-(Azepan-1-yl)phenyl)boronic acid (CAS 1279027-58-5)
- 4-Formylbicyclo[2.2.2]octane-1-carboxylic acid (CAS 96102-85-1)
- Semaglutide Impurity 8 (CAS CATO-C4X-22268)
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