5-(2-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine CAS 439111-04-3
| CAS No. | 439111-04-3 |
| Molecular Formula | C14H9ClF3N3 |
| Molecular Weight | 311.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-(2-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-04-3), a certified reference material (molecular formula C14H9ClF3N3, MW 311.69 g/mol) for analytical method development and quality control.
Structurally, 5-(2-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (C14H9ClF3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 311.69 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3N3 |
| Molecular Weight | 311.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- 5-(3-Chlorophenyl)-2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 439111-02-1)
- Ethyl 6-(4-chlorophenyl)-2-(difluoromethyl)nicotinate (CAS 1708208-56-3)
- Methyl 1-(2-(4-chlorophenyl)-2-hydroxyethyl)-5-(hydroxymethyl)-1H-1,2,3-triazole-4-carboxylate (CAS 1351772-52-5)
- 1-(4-Chlorophenyl)imidazo[2,1-b]quinazoline-2,5(1H,3H)-dione (CAS 62707-35-1)
- 2-(4-Chlorophenyl)-8-methyl-6H-chromeno[8,7-d]oxazol-6-one (CAS 36771-42-3)
- Methyl 2-((4-chlorophenyl)carbamoyl)-6-oxohexahydropyridazine-4-carboxylate (CAS 339096-86-5)
- (2E)-3-(3-Chlorophenyl)-2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-1,2,4-triazol-3-yl}prop-2-enenitrile (CAS 1164520-60-8)
- 3-(4-Chlorophenyl)-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazol-3-yl]acrylonitrile (CAS 1164552-75-3)
Recommended Standards
- 3-[8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]aniline (CAS 860785-05-3)
- 3-(2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-methyl-1H-indole (CAS 1903753-93-4)
- 9-Chloro-6-methoxy-2-(trifluoromethyl)acridine (CAS 811432-17-4)
- 3-((2-Chloro-4-fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 1706455-65-3)
- 5-[(3,6-Dimethoxy-2-nitrophenyl)methylene]-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 860612-27-7)
- 3-{[(Tert-butoxy)carbonyl](cyclopentyl)amino}propanoic acid (CAS 917202-01-8)
- 2-Benzenesulfonamido-3-methylbutanoic acid (CAS 85849-94-1)
- (5E)-2-Mercapto-5-(4-methylbenzylidene)-1,3-thiazol-4(5H)-one 0861AE 33992-80-2 C11H9NOS2 (CAS 33992-80-2)
- 4-(Ethoxycarbonyl)-1-methylpyridin-1-ium iodide (CAS 10129-59-6)
- 7-Amino-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-6-carbonitrile (CAS 890091-74-4)
- Obeticholic Acid impurity 38 (CAS CATO-C4X-115338)
- ETHYL 3-AMINO-5-(TRIFLUOROMETHYL)PICOLINATE (CAS 1393544-93-8)
- 5-Chloro-4-fluoro-2-nitroaniline (CAS 104222-34-6)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
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