6-Chloropyrimidine-4-carboxamide CAS 81333-06-4
| CAS No. | 81333-06-4 |
| Molecular Formula | C5H4ClN3O |
| Molecular Weight | 157.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloropyrimidine-4-carboxamide.
6-Chloropyrimidine-4-carboxamide (CAS 81333-06-4), molecular formula C5H4ClN3O and molecular weight 157.56 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Chloropyrimidine-4-carboxamide (C5H4ClN3O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 157.56 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloropyrimidine-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClN3O |
| Molecular Weight | 157.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrimidine Standards
- 2-Chloropyrimidine-4-carboxamide, 97% (CAS 22536-66-9)
- 2-Chloropyrimidine-5-carboxamide (CAS 856595-94-3)
- 5-Chloropyrimidine-2-carboxamide (CAS 38275-59-1)
- 2-Chloropyrimidine-5-boronic Acid (CAS 1003845-06-4)
- 2-Chloropyrimidine-4-carboxylic Acid (CAS 149849-92-3)
- 2-Chloropyrimidine-5-carboxylic Acid (CAS 374068-01-6)
- 4-Chloropyrimidine-5-carboxylic acid (CAS 933686-33-0)
- 5-Chloropyrimidine-4-carboxylic Acid (CAS 64224-65-3)
Recommended Standards
- 6-Chloropyridazine-3-carboxamide (CAS 66346-83-6)
- N-(2-Chloropyrimidin-5-yl)formamide (CAS 56621-85-3)
- 6-Chloropyridazine-3-carbaldehyde oxime (CAS 716379-11-2)
- N-(6-Chloropyridazin-3-yl)formamide (CAS 35053-58-8)
- 7-Fluorochroman-4-one (CAS 113209-68-0)
- Maraviroc RC3 (CAS 1391048-00-2)
- 1-Cyclopropyl-3-(trifluoromethoxy)benzene (CAS 2060034-65-1)
- 1-Benzyl-4-(ethylamino)piperidine-4-carboxamide (CAS 1027-91-4)
- 1-[(5-chloro-3-ethyl-1-methyl-1H-pyrazol-4-yl)methyl]piperazine (CAS 1315366-21-2)
- 1-Phenyl-6-(pyrrolidin-1-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one (CAS 1280802-52-9)
- 6-(3,4-Dichlorophenyl)pyrimidine-4-carbonitrile, 97% (CAS 1319175-50-2)
- n-(Piperidin-4-yl)pyridazin-3-amine dihydrochloride (CAS 1311315-74-8)
- 5-(Piperidin-4-yl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole (CAS 849925-00-4)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com