2-Chloropyrimidine-4-carboxamide, 97% CAS 22536-66-9
| CAS No. | 22536-66-9 |
| Molecular Formula | C5H4ClN3O |
| Molecular Weight | 157.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Chloropyrimidine-4-carboxamide, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Chloropyrimidine-4-carboxamide, 97% (CAS 22536-66-9), molecular formula C5H4ClN3O and molecular weight 157.56 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloropyrimidine-4-carboxamide, 97% is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 157.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H4ClN3O |
| Molecular Weight | 157.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrimidine Standards
- 2-Chloropyrimidine-5-carboxamide (CAS 856595-94-3)
- 5-Chloropyrimidine-2-carboxamide (CAS 38275-59-1)
- 6-Chloropyrimidine-4-carboxamide (CAS 81333-06-4)
- 2-Chloropyrimidine-5-boronic Acid (CAS 1003845-06-4)
- 2-Chloropyrimidine-4-carboxylic Acid (CAS 149849-92-3)
- 2-Chloropyrimidine-5-carboxylic Acid (CAS 374068-01-6)
- 4-Chloropyrimidine-5-carboxylic acid (CAS 933686-33-0)
- 5-Chloropyrimidine-4-carboxylic Acid (CAS 64224-65-3)
Recommended Standards
- 2-Amino-4-chloropyrimidine-5-carbaldehyde (CAS 848697-17-6)
- 4-Amino-6-chloropyrimidine-5-carboxaldehyde (CAS 14160-93-1)
- 3-Amino-6-chloropyrazine-2-carbaldehyde (CAS 89284-26-4)
- N-hydroxypyrimidine-4-carbimidoyl chloride (CAS 1186089-66-6)
- 4-Fluoro-N-methyl-N-(thiophen-2-ylmethyl)benzenesulfonamide (CAS 923871-23-2)
- (R)-3-(3-bromo-2-fluorophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1993381-19-3)
- 8-Phenyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (CAS 794479-16-6)
- 5-Amino-4-methyl-2-nitrobenzoic acid (CAS 204254-63-7)
- N-allyl-2-phenyl-6-((phenylsulfonyl)methyl)pyrimidin-4-amine (CAS 477867-00-8)
- 2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindole-5-sulfonyl chloride (CAS 2680612-78-4)
- Methyl 6-amino-5-(2,3,5-trichlorophenyl)picolinate (CAS 875051-79-9)
- N-(2-Bromoallyl)acetamide (CAS 500882-05-3)
- 4-Amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one (CAS 123313-07-5)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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