Ibuprofen Impurity 50 CAS 81576-47-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.81576-47-8
Molecular FormulaC21H27NO
Molecular Weight309.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ibuprofen Impurity 50 CAS 81576-47-8 chemical structure

Description

CATO supplies Ibuprofen Impurity 50 (CAS 81576-47-8), a pharmacopoeial impurity reference standard (molecular formula C21H27NO, MW 309.45 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C21H27NO, Ibuprofen Impurity 50 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 309.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H27NO
Molecular Weight309.45 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Nitrogen Atoms1

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