Ibuprofen Impurity 7 CAS 121734-79-0
| CAS No. | 121734-79-0 |
| Molecular Formula | C21H27NO |
| Molecular Weight | 309.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ibuprofen Impurity 7 (CAS 121734-79-0) is a certified pharmaceutical impurity reference standard with the molecular formula C21H27NO and a molecular weight of 309.45 g/mol.
The molecular framework of Ibuprofen Impurity 7 (C21H27NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Ibuprofen Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H27NO |
| Molecular Weight | 309.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Ibuprofen Standards
- Ibuprofen impurity 127 (CAS 105959-56-6)
- Ibuprofen Impurity 39 (CAS 81576-52-5)
- Ibuprofen Impurity 50 (CAS 81576-47-8)
- Ibuprofen Impurity 106 (CAS CATO-C4X-1082106)
- Ibuprofen Impurity 107 (CAS CATO-C4X-1082107)
- Ibuprofen Impurity 108 (CAS CATO-C4X-1082108)
- Ibuprofen Impurity 112 (CAS CATO-C4X-1082112)
- Ibuprofen Impurity 59 (CAS 89878-72-8)
Recommended Standards
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- Roflumilast impurity 22 (CAS 343927-62-8)
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