Levofloxacin Impurity 22 CAS 82419-46-3
| CAS No. | 82419-46-3 |
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 347.34 g/mol gives Levofloxacin Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Levofloxacin Impurity 22 (CAS 82419-46-3) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18FN3O4 and a molecular weight of 347.34 g/mol.
Based on its molecular formula C17H18FN3O4, Levofloxacin Impurity 22 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.34 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Levofloxacin Standards
- Levofloxacin EP Impurity B (CAS 117707-40-1)
- Levofloxacin Impurity 60 (CAS CATO-C4X-137160)
- Levofloxacin Impurity 30 (CAS CATO-C4X-137130)
- Levofloxacin Impurity 35 (CAS 1012310-27-8)
- Levofloxacin EP Impurity G(Levofloxacin USP Related Compound E) (CAS 151250-76-9)
- Levofloxacin Impurity 61 (CAS CATO-C4X-137161)
- Levofloxacin Impurity 89 (CAS CATO-C4X-137189)
- Levofloxacin impurity 67 (CAS CATO-C4X-137167)
Recommended Standards
- Ofloxacin EP Impurity E (CAS 82419-52-1)
- Ciprofloxacin impurity 51 (CAS CATO-C4X-136251)
- Norfloxacin EP Impurity G (CAS 70459-04-0)
- Ciprofloxacin Impurity 41 (CAS CATO-C4X-136241)
- Lurasidone Impurity 22 (CAS 1072-95-3)
- Timolol EP Impurity G (CAS 75202-36-7)
- Paliperidone Impurity 39 (CAS CATO-C4X-1724139)
- 2-(2-Hydroxyethyl)-2h,3h-[1,2,4]triazolo[4,3-a]pyridin-3-one (CAS 56654-49-0)
- 2-(3-Bromophenyl)-2'-iodoacetophenone (CAS 898783-88-5)
- 2-[3-(4-methylphenyl)propanamido]acetic acid (CAS 1098367-46-4)
- 2-Chloro-4-methyl-5-trifluoromethylsulfanylpyridine (CAS 1246466-87-4)
- 5-Bromo-1-(3-chlorobenzyl)-1H-pyrazole (CAS 1427013-90-8)
- (5-Bromo-1H-indol-3-yl)methanamine (CAS 339282-65-4)
- Erythropoietin Mimetic Peptide Sequence 20 (CAS 203397-62-0)
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