Palbociclib Impurity 104 CAS 827022-35-5
| CAS No. | 827022-35-5 |
| Molecular Formula | C33H45N7O4 |
| Molecular Weight | 603.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Palbociclib Impurity 104 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 603.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Palbociclib Impurity 104 (CAS 827022-35-5), a pharmacopoeial impurity reference standard (molecular formula C33H45N7O4, MW 603.75 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C33H45N7O4 |
| Molecular Weight | 603.75 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity 19 (CAS 1941177-47-4)
- Palbociclib Impurity 10 (CAS CATO-C3D-1457)
- Palbociclib Impurity 39 (CAS 866084-31-3)
- Palbociclib impurity 131 (CAS CATO-C4X-1125131)
- Palbociclib Impurity 122 (CAS CATO-C4X-1125122)
- Palbociclib Impurity 102 (CAS CATO-C4X-1125102)
- Palbociclib Impurity 107 (CAS CATO-C4X-1125107)
- Palbociclib Impurity 164 (CAS CATO-C4X-1125164)
Recommended Standards
- N-((S)-(2-(Diphenylphosphino)-5-((4-vinylbenzyl)oxy)phenyl)(phenyl)methyl)-2-methylpropane-2-sulfinamide (CAS 2458268-79-4)
- Revefenacin-d6 (CAS 864750-70-9(unlabelled))
- H-Ala-Leu-Tyr-Leu-bNA (K-1065.0050) (CAS 201985-44-6)
- Chloro(phthalocyaninato)iron (CAS 14285-56-4)
- Propofol Impurity 59 (CAS CATO-C4X-147359)
- Phenylbutazone Impurity 4 (CAS 30923-77-4)
- Moxonidine EP Impurity A (CAS 352457-35-3)
- 4-Fluoro-2-iodoaniline (CAS 61272-76-2)
- 3-Amino-4-hydroxybenzoic acid hydrochloride (CAS 1571-65-9)
- 4-Bromo-3-methylbenzenesulfonamide (CAS 879487-75-9)
- 1-(Furan-2-yl)-2-(piperazin-1-yl)ethan-1-one dihydrochloride (CAS 1306604-95-4)
- 3-Amino-5-(4-fluorophenyl)thiophene-2-carboxamide (CAS 354813-00-6)
- tert-Butyl 5,9-dioxo-1,4-diazaspiro[5.5]undecane-4-carboxylate (CAS 1263475-14-4)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com