Propofol Impurity 59 CAS CATO-C4X-147359
| CAS No. | CATO-C4X-147359 |
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Propofol Impurity 59.
As a process- or degradation-related impurity, Propofol Impurity 59 (CAS CATO-C4X-147359, C13H18O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Propofol Impurity 59 (C13H18O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 222.28 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Propofol Impurity 59 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18O3 |
| Molecular Weight | 222.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Propofol Standards
- Propofol Impurity 21 (CAS 153752-00-2)
- Propofol EP Impurity N (CAS 13423-73-9)
- Propofol Impurity 32 (CAS 161070-01-5)
- Propofol Impurity 33 (CAS CATO-C4X-147333)
- Propofol Impurity 35 (CAS 2215-21-6)
- Propofol Impurity 39 (CAS 100482-27-7)
- Propofol Impurity 46 (CAS CATO-C4X-147346)
- Propofol Impurity 48 (CAS CATO-C4X-147348)
Recommended Standards
- Propofol Impurity 60 (CAS CATO-C4X-147360)
- Propofol Impurity 61 (CAS CATO-C4X-147361)
- Oxymetazoline Impurity 19 (CAS 1895424-66-4)
- Ropivacaine Impurity 19 (CAS 1817657-89-8)
- Epinastine Impurity 38 (CAS CATO-C4X-184038)
- Ceftazidime impurity 120 (CAS CATO-C4X-1212120)
- Ceritinib Impurity 87 (CAS 2976-70-7（free base))
- Ticlopidine Hydrochloride EP Impurity I (CAS 60612-23-9)
- N-(4-Chlorobenzyl)-4-methylaniline (CAS 33863-79-5)
- 2-(ethylamino)-N,N-dimethylacetamide (CAS 97454-95-0)
- Ciprofloxacin Impurity 39 (CAS CATO-C4X-136239)
- 6-(2-Deoxy-5-O-DMT-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido-[4,5-c][1,2]oxazin-7-one (CAS 126128-43-6)
- 8-((5-Methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy)quinolin-5-amine (CAS 919278-22-1)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com