2-Chloro-N-(3,4-dimethoxyphenyl)quinazolin-4-amine CAS 827030-99-9
| CAS No. | 827030-99-9 |
| Molecular Formula | C16H14ClN3O2 |
| Molecular Weight | 315.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Chloro-N-(3,4-dimethoxyphenyl)quinazolin-4-amine (CAS 827030-99-9), a certified reference material (molecular formula C16H14ClN3O2, MW 315.75 g/mol) for analytical method development and quality control.
2-Chloro-N-(3,4-dimethoxyphenyl)quinazolin-4-amine (C16H14ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-(3,4-dimethoxyphenyl)quinazolin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClN3O2 |
| Molecular Weight | 315.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 3-(5-Chloro-2-phenoxyphenyl)-1-methylpyrrolidine-2,4-dione, 97% (CAS 1162120-35-5)
- 3-Chloro-3′-[(cyclopropylamino)carbonyl][1,1′-biphenyl]-4-carboxylic acid (CAS 1261984-00-2)
- Methyl 2-(7-chloro-5-methyl-2-phenylpyrazolo[1,5-a]pyrimidin-6-yl)acetate (CAS 1313377-99-9)
- 2-(3-Chloro-2-oxoindolin-4-yl)ethyl benzoate (CAS 139122-17-1)
- 2-(5-Chloro-2-methyl-4-nitrophenyl)-3,4-dihydronaphthalen-1(2H)-one (CAS 1451449-44-7)
- 5-(3-Chloro-4-((2-methylbenzyl)oxy)phenyl)-1,3,4-oxadiazol-2-amine (CAS 1706451-29-7)
- 4-Chloro-N-(4-fluoro-3-methoxyphenyl)benzene-1-sulfonamide (CAS 1881293-44-2)
- N-[3-Chloro-4-(2-pyridylmethoxy)phenyl]-3-cyanopropanamide (CAS 1956377-33-5)
Recommended Standards
- 2-Chloro-N-(2,5-dimethoxyphenyl)quinazolin-4-amine (CAS 827030-61-5)
- 3-(1,3-benzodioxol-5-yl)-N-(4-chlorobenzyl)acrylamide (CAS 298215-65-3)
- 2-Chloro-N-(2,4-dimethoxyphenyl)quinazolin-4-amine (CAS 524033-57-6)
- 3-(2-(4-Chlorophenoxy)phenyl)-1-methylpyrrolidine-2,4-dione (CAS 912356-07-1)
- Methyl 5-hydroxythiazole-2-carboxylate (CAS 1352395-02-8)
- N-(4-Methoxybenzyl)naphthalen-1-amine (CAS 356536-86-2)
- Methyl 3-bromo-4-(((trifluoromethyl)sulfonyl)oxy)-5-(trimethylsilyl)benzoate (CAS 1242069-33-5)
- 3-(4-Bromophenyl)benzo[c]isoxazole (CAS 1140-36-9)
- 2-(3-aminopropoxy)oxane (CAS 75744-51-3)
- 2-Methyl-4,5,6,7-tetrahydro-2H-indazole-3-carbonyl chloride (CAS 149591-34-4)
- 1-(3-Bromo-2-thienyl)-3-(dimethylamino)-2-propen-1-one (CAS 166196-82-3)
- N-(((9H-fluoren-9-yl)methoxy)carbonyl)-N-hexylglycine (CAS 1374785-50-8)
- 6160-80-1 4-methylumbelliferone beta-D-glucuronide 4-MUG 4-Methylumbelliferyl glucuronide 4-methyl-2-oxo-2H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid 4-Methylumbelliferyl beta-glucuronide 4-Methylumbelliferone glucuronide CHEBI:1904 (CAS 6160-80-1)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com