3-bromocyclobutane-1,1-dicarboxylic acid CAS 827032-78-0
| CAS No. | 827032-78-0 |
| Molecular Formula | C6H7BrO4 |
| Molecular Weight | 223.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 223.02 g/mol gives 3-bromocyclobutane-1,1-dicarboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-bromocyclobutane-1,1-dicarboxylic acid (CAS 827032-78-0), molecular formula C6H7BrO4 and molecular weight 223.02 g/mol, is a CATO reference standard with documented purity and traceability.
3-bromocyclobutane-1,1-dicarboxylic acid (C6H7BrO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-bromocyclobutane-1,1-dicarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H7BrO4 |
| Molecular Weight | 223.02 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
Related bromocyclobutane Standards
- ethyl 3-bromocyclobutane-1-carboxylate (CAS 1934754-13-8)
- Methyl 1-bromocyclobutane-1-carboxylate (CAS 51175-79-2)
- methyl 3-bromocyclobutane-1-carboxylate (CAS 4935-00-6)
- 1-Bromocyclobutane-1-carboxamide (CAS 51175-80-5)
- Benzyl 3-bromocyclobutane-1-carboxylate (CAS 2167366-61-0)
- Bromocyclobutane (CAS 4399-47-7)
Recommended Standards
- 5-Bromo-4-(1,1-difluoroethyl)pyrimidine (CAS 1823642-95-0)
- 4-Bromo-1-(2,2-difluorocyclopropyl)-1H-pyrazole (CAS 2173998-80-4)
- 4-Bromo-3,5-difluorobenzene-1,2-diamine (CAS 1823344-37-1)
- 4-Bromo-2-(difluoromethyl)-6-methylpyrimidine (CAS 2248359-57-9)
- 8-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 338795-36-1)
- (3aR,5 inverted exclamation markaS,7aR)-3 inverted exclamation marka-(4-Ethylphenyl)-dihydro-2,2-dimethyl-spiro[6H-1,3-dioxolo[4,5-c]pyran-6,5 inverted exclamation marka-oxazolidine]-2 inverted exclamation marka,7(4H)-dione 879880-79-2 Shi Epoxidation Oxazolidinone Ethyl Catalyst (CAS 879880-79-2)
- N-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine (CAS 2096341-76-1)
- (3-Chlorophenyl)(ethyl)(imino)-l6-sulfanone (CAS 2060030-24-0)
- N,N-dimethyl-6-(pyrrolidin-2-yl)pyridazin-3-amine dihydrochloride (CAS 1955540-77-8)
- Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite (CAS 128858-43-5)
- Lodiperone (CAS 72444-63-4)
- RMC6236 Intermediate 25 (CAS CATO-CIM-103913)
- 15H-5,11[5′,6′]-Endo-benzimidazoanthra[2,3-d:6,7-d′]diimidazole, 1,5,7,11-tetrahydro- (CAS 1313240-78-6)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com