Furosemide Impurity 41 CAS 137-65-5
| CAS No. | 137-65-5 |
| Molecular Formula | C7H8N2O4S |
| Molecular Weight | 216.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Furosemide Impurity 41 (CAS 137-65-5) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8N2O4S and a molecular weight of 216.21 g/mol.
The molecular framework of Furosemide Impurity 41 (C7H8N2O4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O4S |
| Molecular Weight | 216.21 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Furosemide Standards
- Furosemide Impurity 34 (CAS 6660-65-7)
- Furosemide Impurity 21 (CAS 30170-04-8)
- Furosemide EP Impurity E (CAS 50-84-0)
- Furosemide Impurity 57 (CAS 5428-37-5)
- Furosemide EP Impurity C (CAS 3086-91-7)
- Furosemide Impurity 50 (CAS 64174-54-5)
- Furosemide Impurity 11 (CAS CATO-C4X-140211)
- Furosemide Impurity 12 (CAS 74793-12-7)
Recommended Standards
- Pantoprazole EP Impurity C (CAS 97963-62-7)
- Flurbiprofen EP Impurity E (CAS 137045-30-8)
- Celecoxib Impurity 75 (CAS CATO-C4X-104375)
- Clavulanic Acid Methyl-d3 Ester (CAS CATO-C4X-150116)
- Hydrocortisone Impurity 74 (CAS CATO-C4X-140174)
- Paliperidone Impurity N11 (CAS 95742-20-4)
- Aripiprazole Impurity 38 (CAS CATO-C4X-100838)
- 2-(4-(Dimethylamino)phenyl)-3-methylbutan-2-ol (CAS 28168-87-8)
- 1-(Pyridin-4-ylmethyl)-1,4-diazepane tris(4-methylbenzenesulfonate) (CAS 1185553-75-6)
- 4-Hydroxymandelic Acid (CAS 1198-84-1)
- 4-(6-(3,6-Diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile dihydrochloride (CAS 2222752-06-7)
- 7-Fluoro-6-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1337141-91-9)
- Epalrestat Impurity 15 (CAS CATO-C4X-223615)
- D-[Ala]24-Semaglutide (CAS CATO-C4X-2226126)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com