Esmolol Impurity 12 CAS 83356-60-9
| CAS No. | 83356-60-9 |
| Molecular Formula | C15H23NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Esmolol Impurity 12 (CAS 83356-60-9), a pharmacopoeial impurity reference standard (molecular formula C15H23NO4HCl, MW 317.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Esmolol Impurity 12 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 317.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Esmolol Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H23NO4 HCl |
| Molecular Weight | 317.81 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Esmolol Standards
- Esmolol Impurity 19 (CAS 108260-84-0)
- Esmolol Impurity N2 (CAS 112805-58-0)
- Esmolol Impurity 46 (CAS 112805-66-0)
- (S)-Esmolol HCl (CAS 112923-91-8)
- Esmolol (S)-Isomer (Base) (CAS 115729-56-1)
- Esmolol (R)-Isomer (Base) (CAS 117405-53-5)
- (R)-Esmolol Hydrochloride (CAS 118629-36-0)
- Esmolol Impurity 72 (CAS 1293388-71-2)
Recommended Standards
- Gadobutrol Impurity 183 (CAS CATO-C4X-2120183)
- Fluocinolone Acetonide EP Impurity J (CAS 1361531-95-4)
- Choline Fenofibrate EP Impurity B (CAS 42017-89-0)
- N-(4-bromophenyl)formamide (CAS 2617-78-9)
- Talbutal impurity 1 (CAS CATO-C4X-31041)
- 4-Methoxyphenylacetamide (CAS 6343-93-7)
- ((2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-chloro-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 58865-95-5)
- (1R,2R,4S)-tert-Butyl 2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate (CAS 1260607-47-3)
- 4-Chloro-1,2-dimethyl-1H-imidazo[4,5-c]pyridine (CAS 73576-77-9)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com