Esmolol Impurity N2 CAS 112805-58-0
| CAS No. | 112805-58-0 |
| Molecular Formula | C13H16O4 |
| Molecular Weight | 236.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Esmolol Impurity N2 (CAS 112805-58-0, C13H16O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Esmolol Impurity N2 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 236.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16O4 |
| Molecular Weight | 236.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
Related Esmolol Standards
- Esmolol Impurity 54 (CAS CATO-C4X-189154)
- Esmolol Impurity 67 (CAS CATO-C4X-189167)
- Esmolol Impurity 8 (CAS 81147-94-6)
- Esmolol Impurity 78 (CAS CATO-C4X-189178)
- Esmolol Impurity 48 (CAS CATO-C4X-189148)
- Esmolol Impurity 87 (CAS CATO-C4X-189187)
- Esmolol Impurity 21 (CAS CATO-C4X-189121)
- Esmolol Impurity 96 (CAS CATO-C4X-189196)
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