Propofol Impurity 44 CAS 83420-68-2
| CAS No. | 83420-68-2 |
| Molecular Formula | C25H36O2 |
| Molecular Weight | 368.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Propofol Impurity 44.
Propofol Impurity 44 (CAS 83420-68-2) is a certified pharmaceutical impurity reference standard with the molecular formula C25H36O2 and a molecular weight of 368.55 g/mol.
The molecular framework of Propofol Impurity 44 (C25H36O2) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Propofol Impurity 44 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H36O2 |
| Molecular Weight | 368.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
Related Propofol Standards
- Propofol EP Impurity E (CAS 2416-95-7)
- Propofol β-D-Glucuronide (CAS 114991-26-3)
- Propofol Impurity 20 (CAS 2178-51-0)
- Propofol Impurity 28 (CAS 40388-51-0)
- Propofol Impurity 43 (CAS CATO-C4X-147343)
- Propofol Impurity 51 (CAS CATO-C4X-147351)
- Propofol Impuirity 45 (CAS CATO-C4X-147345)
- Propofol impurity 63 (CAS 110398-11-3)
Recommended Standards
- 2-Butenedioic acid, 2-octadecyl-, (E)- (CAS 94213-56-6)
- Oxymetazoline Impurity 15 (CAS 87079-84-3)
- 1,4-Dinonyl (2Z)-2-butenedioate (CAS 2787-64-6)
- Monostearyl Maleate (CAS 2424-62-6)
- Brivaracetam Impurity 196 (CAS CATO-C4X-2007196)
- Dotinurad Impurity 232 (CAS CATO-C4X-2494232)
- Celecoxib Impurity 57 (CAS CATO-C4X-104357)
- 3-Amino-N-(2-chlorophenyl)-4-(trifluoromethyl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 626228-06-6)
- (1-Cyclohexylethyl)hydrazine (CAS 13324-55-5)
- 2-Adamantan-1-yl-propan-2-ol (CAS 775-64-4)
- Dalilesen impurity 39 (CAS 1505484-96-7)
- 7-Chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinazoline (CAS 57370-21-5)
- 1-(4-(3-Methylpiperidin-1-yl)phenyl)ethan-1-amine (CAS 869945-54-0)
- Bax inhibitor peptide V5 (CAS 579492-81-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com