4-Chloro-5,6-dimethyl-2-phenylthieno[2,3-d]pyrimidine CAS 83548-60-1
| CAS No. | 83548-60-1 |
| Molecular Formula | C14H11ClN2S |
| Molecular Weight | 274.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-5,6-dimethyl-2-phenylthieno[2,3-d]pyrimidine (C14H11ClN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 4-Chloro-5,6-dimethyl-2-phenylthieno[2,3-d]pyrimidine (CAS 83548-60-1), a certified reference material (molecular formula C14H11ClN2S, MW 274.77 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5,6-dimethyl-2-phenylthieno[2,3-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11ClN2S |
| Molecular Weight | 274.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 1-Benzyl-5-chloro-1H-1,3-benzodiazole-2-thiol (CAS 100440-60-6)
- 4-Chloro-2-ethyl-5-phenylthieno[2,3-d]pyrimidine (CAS 1042511-49-8)
- 2-Chloro-3-((4-methylpiperidin-1-yl)sulfonyl)pyridine (CAS 1154872-80-6)
- 2-Chloro-N-cyclohexylpyridine-3-sulfonamide (CAS 1155912-23-4)
- Ethyl 2-(4-chloro-2-(methylthio)pyrimidin-5-yl)-2-methylpropanoate (CAS 1201362-85-7)
- 2-(((5-Chloro-1,2,3-thiadiazol-4-yl)methyl)(cyclopentyl)amino)acetamide (CAS 1210126-98-9)
- 2-(1-((5-Chloro-1,2,3-thiadiazol-4-yl)methyl)piperidin-4-yl)acetamide (CAS 1222983-01-8)
- 2-Chloro-1-methanesulfonyl-1,2,3,4,5,6-hexahydro-[4,4]bipyridinyl (CAS 1316217-42-1)
Recommended Standards
- 4-Chloro-5-(3,4-dimethylphenyl)thieno[2,3-d]pyrimidine (CAS 379241-56-2)
- 4-Chloro-6-methyl-5-(4-methylphenyl)thieno[2,3-d]pyrimidine (CAS 610274-05-0)
- 4-chloro-3-(piperidin-1-ylsulfonyl)aniline (CAS 560995-29-1)
- 4-Chloro-N-methyl-5-(methylthio)-6-morpholinopyrimidin-2-amine (CAS 83199-51-3)
- Pomalidomide-PEG5-OH (CAS 2140807-34-5)
- 2-(2-Bromopyrimidin-5-yl)acetic acid (CAS 1379330-42-3)
- 1-(4-Fluorophenyl)-4-methyl-1H-pyrazolo[3,4-d]pyridazine-7-thiol (CAS 1105198-21-7)
- 3-(Methylsulfonamido)benzaldehyde (CAS 55512-05-5)
- Methyl 2-amino-3-(2-chlorophenyl)propanoate hydrochloride (CAS 37844-15-8)
- 4-(5-Fluoro-1,3-dioxoisoindolin-2-yl)benzoic acid (CAS 299963-58-9)
- Methyl 2-amino-4-bromo-3-fluorobenzoate (CAS 1825390-63-3)
- (R)-3-amino-6,8-difluoro-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one (CAS 2306249-49-8)
- N-Desethyl Bimatoprost (CAS 155205-89-3)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
Why CATO?
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