Naproxen EP Impurity C CAS 84236-26-0
| CAS No. | 84236-26-0 |
| Molecular Formula | C14H13BrO3 |
| Molecular Weight | 309.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 309.16 g/mol gives Naproxen EP Impurity C distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Naproxen EP Impurity C (CAS 84236-26-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13BrO3 and a molecular weight of 309.16 g/mol.
Structurally, Naproxen EP Impurity C (C14H13BrO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 309.16 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Naproxen EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H13BrO3 |
| Molecular Weight | 309.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Br-containing |
Related Naproxen Standards
- Naproxen Impurity 20 (CAS 27655-95-4)
- Naproxen Glycerol Ester Impurity (CAS 38835-17-5)
- Naproxen Impurity 34 (CAS CATO-C4X-170834)
- Naproxen Impurity 35 (CAS CATO-C4X-170835)
- Naproxen Impurity 38 (CAS 2514763-96-1)
- Naproxen Impurity 16 (CAS CATO-C4X-170816)
- Naproxen Impurity 18 (CAS 2601735-81-1)
- Naproxen Impurity 17 (CAS CATO-C4X-170817)
Recommended Standards
- 4-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)benzonitrile (CAS 1205683-41-5)
- 959578-19-9 Ethyl 5-bromo-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate DTXSID40377228 (CAS 959578-19-9)
- n,n-Diethyl-5-iodothiophene-3-carboxamide (CAS 1333648-48-8)
- N-(6-Bromo-8-ethyl-2-hydroxyquinolin-5-yl)acetamide (CAS 91761-88-5)
- Norepinephrine Impurity 129 (CAS CATO-C4X-1514129)
- Palonosetron Impurity 21 2HCl (CAS 2216746-63-1（free base）)
- Acetylcysteine impurity 62 (CAS 64524-84-1)
- 7-((3-Methoxybenzyl)oxy)-2,3-dihydrocyclopenta[c]chromen-4(1H)-one (CAS 374765-29-4)
- Ethyl E-N-Boc-Piperidin-4-ylacrylate (CAS 198895-61-3)
- methyl 3-[bis(tert-butoxycarbonyl)amino]-5-bromo-pyridine-2-carboxylate (CAS 2615357-68-9)
- 1-Bromo-4-iodo-5-methoxy-2-nitrobenzene (CAS 1934921-47-7)
- 2’-(4,4-Dimethyl-1-piperidinyl)acetophenone (CAS 262861-04-1)
- Tetradec-13-enoic acid (CAS 7331-03-5)
- Neuropeptide Y, porcine (CAS 82785-45-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com