5-(3-Chloro-5-fluorophenyl)-5-oxovaleric acid CAS 845790-48-9
| CAS No. | 845790-48-9 |
| Molecular Formula | C11H10ClFO3 |
| Molecular Weight | 244.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(3-Chloro-5-fluorophenyl)-5-oxovaleric acid.
5-(3-Chloro-5-fluorophenyl)-5-oxovaleric acid (CAS 845790-48-9), molecular formula C11H10ClFO3 and molecular weight 244.65 g/mol, is a CATO reference standard with documented purity and traceability.
5-(3-Chloro-5-fluorophenyl)-5-oxovaleric acid (C11H10ClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(3-Chloro-5-fluorophenyl)-5-oxovaleric acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10ClFO3 |
| Molecular Weight | 244.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-ethoxy-5-fluorocinnamic acid (CAS 1017779-08-6)
- 2-Chloro-6-methoxy-4-nitrobenzo[d]thiazole (CAS 1188227-45-3)
- Methyl 4-(4-chloro-3-fluorophenyl)-4-oxobutanoate (CAS 1247500-98-6)
- Ethyl 3-(3-chloro-5-fluorophenyl)-3-oxopropanoate (CAS 1260763-41-4)
- Ethyl 3-(4-chloro-3-fluorophenyl)-3-oxopropanoate (CAS 1260808-42-1)
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Recommended Standards
- 5-(3-Chloro-4-fluorophenyl)-5-oxopentanoic acid (CAS 845790-41-2)
- 5-(4-Chloro-2-fluorophenyl)-5-oxovaleric acid (CAS 951889-56-8)
- 5-(2-Chloro-6-fluorophenyl)-5-oxovaleric acid (CAS 951891-31-9)
- 5-(4-Chloro-3-fluorophenyl)-5-oxovaleric acid (CAS 845790-44-5)
- 2-Amino-6-methyl-4,5,6,7-tetrahydro-thieno[2,3-c]pyridine-3-carboxylic acid (CAS 842968-58-5)
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