1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one CAS 845823-15-6

Purity 97%+In StockPharmaceutical Standards
CAS No.845823-15-6
Molecular FormulaC8H3ClF4O
Molecular Weight226.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one CAS 845823-15-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 226.56 g/mol gives 1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one (CAS 845823-15-6) is a high-purity analytical reference standard with the molecular formula C8H3ClF4O and a molecular weight of 226.56 g/mol.

The molecular framework of 1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one (C8H3ClF4O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 1-(4-Chloro-3-fluorophenyl)-2,2,2-trifluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H3ClF4O
Molecular Weight226.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl-containing

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