1-(Trimethylsilyl)-3-chloro-4-fluorobenzene CAS 845823-20-3
| CAS No. | 845823-20-3 |
| Molecular Formula | C9H12ClFSi |
| Molecular Weight | 202.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(Trimethylsilyl)-3-chloro-4-fluorobenzene.
CATO supplies 1-(Trimethylsilyl)-3-chloro-4-fluorobenzene (CAS 845823-20-3), a certified reference material (molecular formula C9H12ClFSi, MW 202.73 g/mol) for analytical method development and quality control.
Structurally, 1-(Trimethylsilyl)-3-chloro-4-fluorobenzene (C9H12ClFSi) contains fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 202.73 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Trimethylsilyl)-3-chloro-4-fluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12ClFSi |
| Molecular Weight | 202.73 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Trimethylsilyl Standards
- 1-(Trimethylsilyl)-3-chloro-5-fluorobenzene (CAS 845823-23-6)
- Trimethylsilyl 2-chloro-2,2-difluoroacetate (CAS 1700654-90-5)
- 4-((Trimethylsilyl)ethynyl)picolinaldehyde (CAS 1196151-87-7)
- 6-((Trimethylsilyl)ethynyl)nicotinaldehyde (CAS 1196156-38-3)
- (S)-5-(((trimethylsilyl)oxy)methyl)morpholin-3-one (CAS 1616862-23-7)
- 6-((Trimethylsilyl)ethynyl)picolinaldehyde (CAS 183438-94-0)
- 2-((Trimethylsilyl)ethynyl)nicotinaldehyde (CAS 222167-42-2)
- 3-((Trimethylsilyl)ethynyl)pyridine-2-carbaldehyde (CAS 222168-23-2)
Recommended Standards
- (4-Chloro-3-fluorophenyl)trimethylsilane (CAS 845823-22-5)
- (4-Chloro-2-fluorophenyl)trimethylsilane (CAS 153357-87-0)
- 3-(1-Chlorobutyl)-2,5-dimethylthiophene (CAS 1308106-91-3)
- Benzene, 1-chloro-3-fluoro-2-(trimethylsilyl)- (CAS 133117-45-0)
- 2-(4-chlorobenzylamino)phenol (CAS 13313-17-2)
- 1-(4,6-Diamino-1,3,5-triazin-2-yl)-2-phenylethanone (CAS 197571-72-5)
- Benzyl (1,2,3,4-tetrahydroisoquinolin-7-yl)carbamate (CAS 1139884-67-5)
- 1-Chloro-4-(2-fluorophenoxy)benzene (CAS 1881295-16-4)
- 7,9-dimethyl-2,3,4,5-tetrahydro-1-benzoxepin-5-one (CAS 206435-79-2)
- 2-(3-Chloro-4-methylbenzoyl)-N-methylhydrazine-1-carbothioamide (CAS 695199-54-3)
- 2-Amino-10,11-dimethoxy-7,8,12b,13-tetrahydro-5H-1,3,6-triazatetraphen-5-one (CAS 685106-53-0)
- Methyl cis-6-{[(tert-Butoxy)carbonyl]amino}cyclohex-3-ene-1-carboxylate (CAS 836607-50-2)
- 1-[(tert-Butoxy)methyl]-2-chlorobenzene (CAS 56636-81-8)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
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