1-(Trimethylsilyl)-3-chloro-5-fluorobenzene CAS 845823-23-6
| CAS No. | 845823-23-6 |
| Molecular Formula | C9H12ClFSi |
| Molecular Weight | 202.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Trimethylsilyl)-3-chloro-5-fluorobenzene (CAS 845823-23-6) is a high-purity analytical reference standard with the molecular formula C9H12ClFSi and a molecular weight of 202.73 g/mol.
The molecular framework of 1-(Trimethylsilyl)-3-chloro-5-fluorobenzene (C9H12ClFSi) is characterized by fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(Trimethylsilyl)-3-chloro-5-fluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H12ClFSi |
| Molecular Weight | 202.73 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Trimethylsilyl Standards
- 1-(Trimethylsilyl)-3-chloro-4-fluorobenzene (CAS 845823-20-3)
- Trimethylsilyl 2-chloro-2,2-difluoroacetate (CAS 1700654-90-5)
- 4-((Trimethylsilyl)ethynyl)picolinaldehyde (CAS 1196151-87-7)
- 6-((Trimethylsilyl)ethynyl)nicotinaldehyde (CAS 1196156-38-3)
- (S)-5-(((trimethylsilyl)oxy)methyl)morpholin-3-one (CAS 1616862-23-7)
- 6-((Trimethylsilyl)ethynyl)picolinaldehyde (CAS 183438-94-0)
- 2-((Trimethylsilyl)ethynyl)nicotinaldehyde (CAS 222167-42-2)
- 3-((Trimethylsilyl)ethynyl)pyridine-2-carbaldehyde (CAS 222168-23-2)
Recommended Standards
- 3-(1-Chlorobutyl)-2,5-dimethylthiophene (CAS 1308106-91-3)
- (4-Chloro-3-fluorophenyl)trimethylsilane (CAS 845823-22-5)
- 2-(3-(Chloromethyl)pentyl)thiophene (CAS 1478956-73-8)
- (4-Chloro-2-fluorophenyl)trimethylsilane (CAS 153357-87-0)
- (3-Amino-4-methylpiperidin-1-yl)(tetrahydrofuran-3-yl)methanone (CAS 1339495-36-1)
- 2-Chloro-4-(piperazin-1-yl)pyrimidine (CAS 174728-03-1)
- 4-Bromo-2-chloro-3-(difluoromethyl)pyridine-6-acetic acid (CAS 1805356-36-8)
- 1-[(tert-butoxy)carbonyl]-3-hydroxypyrrolidine-3-carboxylic acid (CAS 1067239-08-0)
- 2-(4-Isopropylphenoxy)butanoic acid (CAS 161790-36-9)
- 4-Bromo-1-((methylsulfonyl)methyl)-2-nitrobenzene (CAS 651780-41-5)
- Methyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-1-oxo-1,2-dihydroisoquinoline-4-carboxylate (CAS 339106-16-0)
- Dichloroacetic Acid (CAS 79-43-6)
- Ethyl 3-ethoxy-2,2-difluoro-3-hydroxypropanoate (CAS 141546-97-6)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com