Bortezomib Impurity 64 CAS 847644-46-6

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.847644-46-6
Molecular FormulaC17H31BN2O3
Molecular Weight322.25 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bortezomib Impurity 64 CAS 847644-46-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bortezomib Impurity 64.

As a process- or degradation-related impurity, Bortezomib Impurity 64 (CAS 847644-46-6, C17H31BN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Bortezomib Impurity 64 (C17H31BN2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Bortezomib Impurity 64 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC17H31BN2O3
Molecular Weight322.25 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1987
Nitrogen Atoms2

Related Bortezomib Standards

Recommended Standards

Why CATO?