Bortezomib Impurity 3 CAS 289472-78-2
| CAS No. | 289472-78-2 |
| Molecular Formula | C19H24N4O3 |
| Molecular Weight | 356.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bortezomib Impurity 3.
As a process- or degradation-related impurity, Bortezomib Impurity 3 (CAS 289472-78-2, C19H24N4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H24N4O3, Bortezomib Impurity 3 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 356.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bortezomib Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H24N4O3 |
| Molecular Weight | 356.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
Related Bortezomib Standards
- Bortezomib Impurity 4 (CAS 289472-81-7)
- Bortezomib Impurity 20 (CAS 862894-96-0)
- Bortezomib Impurity 15 (CAS 275374-67-9)
- Bortezomib Impurity 19 (CAS CATO-C4X-107219)
- Bortezomib Impurity 30 (CAS 2379402-85-2)
- Bortezomib Impurity 52 (CAS CATO-C4X-107252)
- Bortezomib Impurity 65 (CAS CATO-C4X-107265)
- Bortezomib Impurity 13 (CAS 1446194-56-4)
Recommended Standards
- 99694-90-3 Methyl (19S)-12,19-dihydroxy-2,16-didehydrocuran-17-oate (CAS 99694-90-3)
- 1-benzyl-N-(4-methoxyphenyl)-1H-indole-3-carboxamide 860611-44-5 KS-00002YJ3 (CAS 860611-44-5)
- Indobufen Impurity 57 (CAS CATO-C4X-179257)
- tert-Butyl N-({[4-(benzyloxy)phenyl]carbamoyl}methyl)carbamate (CAS 220741-24-2)
- Benzbromarone EP Impurity A (CAS 94729-09-6)
- Tiotropium impurity 46 (CAS 7688-76-8)
- Ixazomib Impurity 35 (CAS CATO-C4X-126735)
- N-Butyl-N-methylpyrrolidin-3-amine (CAS 713141-69-6)
- 3-(4-(2-Carboxy)-pyridyl)-L-alanine (CAS 112055-80-8)
- 7-(1,1-Dimethylethyl)-3-(2,6-dimethylphenyl)-2,3,5,6,7,8-hexahydro-2-thioxo[1]benzothieno[2,3-d]pyrimidin-4(1H)-one (CAS 744227-08-5)
- 4-(4-Hydroxy-6-methyl-2-oxopyridin-1(2H)-yl)-N-(2-(pyridin-3-yl)-1H-benzo[d]imidazol-6-yl)butanamide (CAS 1574403-89-6)
- 3-Bromo-4-methyl-N-(2,2,2-trifluoroethyl)aniline (CAS 1343245-72-6)
- 3-(7-Methyl-1H-indol-3-yl)propan-1-ol (CAS 29957-87-7)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com