Rosuvastatin EP Impurity M(Sodium Salt) CAS 847849-66-5(free base)
| CAS No. | 847849-66-5(free base) |
| Molecular Formula | C22H28N3O6S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rosuvastatin EP Impurity M(Sodium Salt) is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Rosuvastatin EP Impurity M(Sodium Salt) (CAS 847849-66-5(free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28N3O6SNa and a molecular weight of 485.53 g/mol.
Rosuvastatin EP Impurity M(Sodium Salt) (C22H28N3O6SNa) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rosuvastatin EP Impurity M(Sodium Salt) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28N3O6S Na |
| Molecular Weight | 485.53 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rosuvastatin Standards
- Rosuvastatin Impurity 205 (CAS 1007871-85-3)
- Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (CAS 1024064-70-7)
- Rosuvastatin Impurity 267 (CAS 1031246-43-1)
- Rosuvastatin Impurity 19 (CAS 1035595-71-1)
- Rosuvastatin Impurity 27 (CAS 1044518-75-3)
- Rosuvastatin Impurity 192 (CAS 1092844-00-2)
- Rosuvastatin Impurity 123 (CAS 1112048-62-0)
- Rosuvastatin Impurity 37 (CAS 1197348-98-3)
Recommended Standards
- Rimegepant Impurity 41 (CAS CATO-C4X-248741)
- Ivabradine impurity 60 (CAS CATO-C4X-111960)
- Levocabastine EP Impurity I (CAS CATO-C4X-22899)
- 2-Chloroethyl linoleate (CAS 25525-76-2)
- 2-Acetylamino-4-chlorophenol (CAS 26488-93-7)
- 2-ethyl-4-methyl-1,3-thiazol-5-amine dihydrochloride (CAS 1607316-02-8)
- tert-Butyl (1,2-dicyclopropyl-2-hydroxyethyl)carbamate (CAS 2147943-46-0)
- Triclabendazole Impurity 4 (CAS 145770-89-4)
- Tert-butyl 9-(aminomethyl)-3-azabicyclo[3.3.1]Nonane-3-carboxylate (CAS 1357354-27-8)
- Sperm Peptide P10G (H-2424.0001) (CAS 137353-73-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com