6-Hydroxy-4-(trifluoromethyl)nicotinic acid CAS 849020-87-7
| CAS No. | 849020-87-7 |
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Hydroxy-4-(trifluoromethyl)nicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
6-Hydroxy-4-(trifluoromethyl)nicotinic acid (CAS 849020-87-7) is a high-purity analytical reference standard with the molecular formula C7H4F3NO3 and a molecular weight of 207.11 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 6-Hydroxy-4-(trifluoromethyl)nicotinic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 4-Hydroxy-6-(trifluoromethyl)nicotinic acid (CAS 1060810-79-8)
- 4-hydroxy-5-(trifluoromethyl)pyridine-3-carboxylic acid (CAS 1211530-53-8)
- 3-Hydroxy-6-(trifluoromethyl)picolinic acid (CAS 1214362-36-3)
- 2-Hydroxy-3-(trifluoromethyl)isonicotinic acid (CAS 1227514-41-1)
- 2-Hydroxy-5-(trifluoromethyl)isonicotinic acid (CAS 1227594-58-2)
- 4-Hydroxy-6-(trifluoromethyl)picolinic acid (CAS 1256789-28-2)
- 5-Hydroxy-6-(trifluoromethyl)picolinic acid (CAS 1256809-93-4)
- 3-Hydroxy-2-(trifluoromethyl)isonicotinic acid (CAS 135245-01-1)
Recommended Standards
- Apalutamide Impurity 64 (CAS 1211542-14-1)
- 1-(2-Bromoethyl)-4-methylpiperazinedihydrobromide (CAS 801152-34-1)
- Apalutamide Impurity 44 (CAS 1121056-94-7)
- (3,5-Dichlorophenyl)(ethyl)sulfane (CAS 101079-92-9)
- 2-((5-(4-Hydroxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-(naphthalen-2-yl)-N-phenylacetamide (CAS 482646-89-9)
- Phenylmethylsiloxane-dimethylsiloxane copolymers cst 50 (CAS 63148-52-7)
- Ethyl 4-(2-((1-phenyl-1H-tetrazol-5-yl)thio)acetamido)benzoate (CAS 329078-93-5)
- 4-(3,4-Dimethoxy-phenyl)-thiazol-2-ylamine (CAS 51837-85-5)
- tert-butyl N-[(5-bromo-1,3,4-thiadiazol-2-yl)methyl]carbamate (CAS 1454906-51-4)
- 6-Chloro-3-nitroimidazo[1,2-a]pyridine (CAS 25045-84-5)
- 5-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1190320-25-2)
- 4-(3-Fluorophenyl)pyridine (CAS 39795-59-0)
- 2-Ethyl-4-nitro-1H-benzo[d]imidazole (CAS 101236-92-4)
- Renin Inhibitor Peptide (CAS 50410-01-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com