2-(Chloromethyl)-5-(5-methylthiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one CAS 851116-05-7
| CAS No. | 851116-05-7 |
| Molecular Formula | C12H9ClN2OS2 |
| Molecular Weight | 296.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Chloromethyl)-5-(5-methylthiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 851116-05-7), a certified reference material (molecular formula C12H9ClN2OS2, MW 296.80 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Chloromethyl)-5-(5-methylthiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one (C12H9ClN2OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Chloromethyl)-5-(5-methylthiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H9ClN2OS2 |
| Molecular Weight | 296.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 2-(1-Chloroethyl)-5-(thiophen-2-yl)-3h,4h-thieno[2,3-d]pyrimidin-4-one (CAS 733031-24-8)
- 2-(Methylthio)-5-(phenylthio)pyrimidine-4-carbonyl chloride (CAS 61727-11-5)
- 2-Chloro-1-(4-(2-isopropyl-6-methylpyrimidin-4-yl)piperazin-1-yl)ethan-1-one (CAS 1306606-72-3)
- 3-(4-Chlorophenyl)-2-mercapto-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one (CAS 887201-73-2)
- 6-hydrazinyl-2-methylpyrimidin-4-ol (CAS 29939-38-6)
- 5-Amino-1-(2-chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1416345-60-2)
- (3-Bromo-5-chlorophenyl)dimethylphosphine oxide (CAS 2759950-57-5)
- 5-Cyclopropoxy-2-nitropyridine (CAS 1243459-53-1)
- 2-Isopropyl-1H-imidazole-4,5-dicarbonitrile (CAS 52685-70-8)
- (Z)-1,4-dibromo-1,1,2-trifluorobut-2-ene (CAS 137906-27-5)
- 6-Chloro-N-methylpyridazin-3-amine (CAS 14959-32-1)
- rel-(4R,4′R)-4,4′,5,5′-Tetrahydro-4,4′-bis(phenylmethyl)-2,2′-bioxazole (CAS 188255-29-0)
- Methyl 3-nitro-1H-pyrrolo[3,2-b]pyridine-5-carboxylate (CAS 1190310-77-0)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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