1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrophenyl)piperazine CAS 851472-82-7
| CAS No. | 851472-82-7 |
| Molecular Formula | C23H21F2N3O2 |
| Molecular Weight | 409.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 409.43 g/mol gives 1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrophenyl)piperazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrophenyl)piperazine (CAS 851472-82-7), molecular formula C23H21F2N3O2 and molecular weight 409.43 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-[Bis(4-fluorophenyl)methyl]-4-(4-nitrophenyl)piperazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 409.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H21F2N3O2 |
| Molecular Weight | 409.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (CAS 439081-02-4)
- trans-1-(4-Fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (CAS 947332-80-1)
- (S)-5-(1-(1-(4-Fluorophenyl)ethyl)-1H-[1,2,3]triazolo[4,5-c]quinolin-8-yl)benzo[d]oxazole (CAS 2123491-32-5)
- N-(2-Fluorophenyl)-2-((7-methyl-4-oxo-8-phenyl-3,4-dihydropyrazolo[1,5-a][1,3,5]triazin-2-yl)thio)acetamide (CAS 946247-48-9)
- 1-(4-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)-2-(4-methylphenoxy)ethan-1-one (CAS 1775455-69-0)
- N-(4-fluorophenyl)-1,3-dimethyl-5-((3-(trifluoromethyl)phenyl)thio)-1H-pyrazole-4-carboxamide (CAS 303997-97-9)
- 1-[2-[bis(4-Fluorophenyl)methoxy]ethyl]-4-(pyridinyl)-piperazine (CAS 154558-38-0)
- 3-Ethyl-5-((3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one (CAS 302938-07-4)
Recommended Standards
- 16,18-Dioxo-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl 3-methylbenzoate (CAS 478029-44-6)
- (6S,9R)-6-(4-Hydroxybenzyl)-2,2,9-trimethyl-4,7,10-trioxo-3-oxa-5,8,11-triazatridecan-13-oic acid (CAS 64410-47-5)
- 16,18-Dioxo-17-azapentacyclo[6.6.5.0^{2,7}.0^{9,14}.0^{15,19}]nonadeca-2(7),3,5,9(14),10,12-hexaen-17-yl 4-methylbenzoate (CAS 478029-40-2)
- 1-Methyl 4-prop-2-en-1-yl (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanedioate (CAS 170943-09-6)
- 2-(3-Iodophenyl)-5-methyl-1,3,4-oxadiazole (CAS 41421-02-7)
- (3-((dimethylamino)methyl)phenyl)boronic acid hydrochloride (CAS 1485417-01-3)
- 4-[(butan-2-yl)sulfamoyl]benzoic acid (CAS 436091-85-9)
- N,N,2,5-Tetramethylpyrazolo[1,5-a]pyrimidin-7-amine (CAS 136549-14-9)
- Ethyl (2R)-2-methyl-5-(propan-2-ylidene)cyclopentane-1-carboxylate (CAS 623935-92-2)
- Tert-butyl 7-fluoro-4,5-dihydro-3H-spiro[benzo[b][1,4]oxazepine-2,4'-piperidine]-1'-carboxylate (CAS 1262757-35-6)
- 6-(2-Hydroxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 55982-10-0)
- 1,5-Diazabicyclo[3.2.2]nonane-6-carboxylic acid dihydrochloride (CAS 1423024-32-1)
- Phosphoramidic acid, N-(aminoiminomethyl)- (CAS 3019-36-1)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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