2-Chloro-6-fluoro-N-(2-methoxyphenyl)-N-((2-oxopyrrolidin-1-yl)methyl)benzamide CAS 852132-09-3
| CAS No. | 852132-09-3 |
| Molecular Formula | C19H18ClFN2O3 |
| Molecular Weight | 376.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-fluoro-N-(2-methoxyphenyl)-N-((2-oxopyrrolidin-1-yl)methyl)benzamide.
2-Chloro-6-fluoro-N-(2-methoxyphenyl)-N-((2-oxopyrrolidin-1-yl)methyl)benzamide (CAS 852132-09-3) is a high-purity analytical reference standard with the molecular formula C19H18ClFN2O3 and a molecular weight of 376.81 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-6-fluoro-N-(2-methoxyphenyl)-N-((2-oxopyrrolidin-1-yl)methyl)benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 376.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-fluoro-N-(2-methoxyphenyl)-N-((2-oxopyrrolidin-1-yl)methyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H18ClFN2O3 |
| Molecular Weight | 376.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-N-[(naphthalen-1-yl)methyl]-2-nitrobenzene-1-sulfonamide (CAS 1022360-31-1)
- 2-Chloro-4-fluoro-N-(4-(2-morpholino-2-oxoethyl)phenyl)benzamide (CAS 1070960-22-3)
- 2-((1-(3-Chloro-4-methylphenyl)-2,5-dioxopyrrolidin-3-yl)thio)nicotinic acid (CAS 881483-69-8)
- Ethyl 1-[(4-chloro-3-nitrophenyl)sulfonyl]-4-piperidinecarboxylate (CAS 291292-03-0)
- 5-Chloro-N2-(4-fluorobenzyl)-N4-(5-isopropoxy-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (CAS 1447605-97-1)
- 4-Chloro-7-(3-morpholinopropoxy)-6-nitroquinoline-3-carbonitrile (CAS 919482-04-5)
- 5-Chloro-1,3-dimethyl-N-(2-morpholino-2-oxo-1-phenylethyl)-1H-pyrazole-4-carboxamide (CAS 1030609-39-2)
- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497921-66-1)
Recommended Standards
- 2-[(4-Chlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)pyridine-3-carboxamide (CAS 400078-98-0)
- 6-(2-(4-Chlorophenylsulfonamido)-2-oxoacetamido)hexanoic acid (CAS 701210-22-2)
- (5Z)-5-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-1,3-thiazolidine-2,4-dione (CAS 860783-86-4)
- Flutazolam (CAS 27060-91-9)
- 2-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]methyl}benzoic acid (CAS 733795-51-2)
- N-(3-fluorobenzyl)-N-methylglycine (CAS 1036577-89-5)
- Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) (CAS 131334-43-5)
- 2-Hydroxyisonicotinohydrazide (CAS 98140-91-1)
- (R)-Methyl 3-((tert-butoxycarbonyl)amino)-2-methylpropanoate (CAS 182486-32-4)
- Tetradecylthioacetic Acid (CAS 2921-20-2)
- 5-[2-(2-methylthiazol-4-yl)ethynyl]isoxazolo[5,4-b]pyridin-3-amine (CAS 2524947-36-0)
- tert-butyl N-[1-(methylsulfanyl)propan-2-yl]carbamate (CAS 1598322-55-4)
- 3-Amino-N-(pyridin-3-ylmethyl)propanamide (CAS 271591-66-3)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
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