Edoxaban impurity 135 CAS 852291-42-0
| CAS No. | 852291-42-0 |
| Molecular Formula | C7H9BrN2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Edoxaban impurity 135 (C7H9BrN2SC7H8O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Edoxaban impurity 135 (CAS 852291-42-0), a pharmacopoeial impurity reference standard (molecular formula C7H9BrN2SC7H8O3S, MW 405.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Edoxaban impurity 135 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H9BrN2S C7H8O3S |
| Molecular Weight | 405.32 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Edoxaban Standards
- Edoxaban Impurity 73 (CAS 1057651-37-2)
- Edoxaban Impurity 7 (CAS 1072-98-6)
- Edoxaban Impurity 71 (CAS 1093351-29-1)
- Edoxaban Impurity N8 HCl (CAS 1190971-73-3)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- Edoxaban Tosylate Monohydrate (CAS 1229194-11-9)
Recommended Standards
- Blonanserin Impurity 13 (CAS 2518376-10-6)
- Minoxidil Impurity 47 (CAS 22694-45-7)
- Mirabegron Impurity 15 (CAS CATO-C4X-103215)
- Mitoxantrone Impurity 17 (CAS CATO-C4X-103417)
- 4-(5-Bromothiophen-2-yl)-2,6-dichloropyrimidine (CAS 1482445-82-8)
- 763863-61-2 {3-[(Morpholin-4-yl)methyl]phenyl}(phenyl)methanone DTXSID80607773 (CAS 763863-61-2)
- N-(1-(4-Methoxyphenyl)-3-((4-methoxyphenyl)amino)-3-oxoprop-1-en-2-yl)furan-2-carboxamide (CAS 304000-68-8)
- 2-Methyl-3-(methylthio)benzoic acid (CAS 1149384-42-8)
- Levofloxacin Impurity 46 (CAS CATO-C4X-137146)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com