Edoxaban Impurity N8 HCl CAS 1190971-73-3
| CAS No. | 1190971-73-3 |
| Molecular Formula | C7H8N2O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Edoxaban Impurity N8 HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Edoxaban Impurity N8 HCl (CAS 1190971-73-3), a pharmacopoeial impurity reference standard (molecular formula C7H8N2O2SHCl, MW 220.67 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O2S HCl |
| Molecular Weight | 220.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban Impurity 73 (CAS 1057651-37-2)
- Edoxaban Impurity 7 (CAS 1072-98-6)
- Edoxaban Impurity 71 (CAS 1093351-29-1)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- Edoxaban Tosylate Monohydrate (CAS 1229194-11-9)
- Edoxaban Impurity 79 (CAS 1241725-84-7)
Recommended Standards
- Epinephrine Impurity 27 (CAS 37491-94-4)
- CAS 1361398-65-3 (CAS 1361398-65-3)
- Norethisterone EP Impurity E (CAS 79727-03-0)
- 2-(Cyano(1H-1,2,4-triazol-1-yl)methyl)benzonitrile (CAS 400086-49-9)
- Ezetimibe Impurity 43 (CAS CATO-C4X-109843)
- 2-(Tert-butyl) 3-methyl (3S,6R)-6-fluoro-2-azabicyclo[2.2.1]Heptane-2,3-dicarboxylate (CAS 2177255-15-9)
- 4-Cyclopropoxy-2-methoxy-5-(methylthio)pyridine (CAS 1243454-81-0)
- (S)-1-Ethyl-3-methyl-piperazine dihydrochloride (CAS 1630082-91-5)
- 3-Butoxy-N-[4-(2-ethoxyethoxy)benzyl]aniline (CAS 1040683-47-3)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com