Pitolisant Impurity 43 CAS 85356-69-0
| CAS No. | 85356-69-0 |
| Molecular Formula | C9H10I2 |
| Molecular Weight | 371.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Pitolisant Impurity 43 (CAS 85356-69-0, C9H10I2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pitolisant Impurity 43 (C9H10I2) contains iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Pitolisant Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H10I2 |
| Molecular Weight | 371.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | I-containing |
Related Pitolisant Standards
- Pitolisant impurity 02 (CAS 157355-75-4)
- Pitolisant Impurity 42 (CAS CATO-C4X-252042)
- Pitolisant impurity 11 (CAS CATO-C4X-252011)
- Pitolisant Impurity 46 (CAS CATO-C4X-252046)
- Pitolisant Impurity 1 (CAS CATO-C4X-25201)
- Pitolisant impurity 23 (CAS CATO-C4X-252023)
- Pitolisant impurity 26 (CAS CATO-C4X-252026)
- Pitolisant impurity 29 (CAS CATO-C4X-252029)
Recommended Standards
- 2,4-Diiodo-1,3,5-trimethylbenzene (CAS 53779-84-3)
- 1-[Tris(propan-2-yl)silyl]-1H-indole-6-sulfonyl chloride (CAS 912846-33-4)
- 1-IODO-2-(IODOMETHYL)-4,5-DIMETHYLBENZENE (CAS 1822674-60-1)
- 2,6-Dibromo-N-(2-nitrophenyl)aniline (CAS 2448398-05-6)
- Fluralaner Impurity 19 (CAS CATO-C4X-218019)
- Tofacitinib Impurity 7 (CAS 1616761-00-2)
- Rosuvastatin Impurity 96 (CAS 521974-00-5)
- (E)-3-(dimethylamino)-1-(4-(phenylsulfinyl)phenyl)prop-2-en-1-one (CAS 321432-56-8)
- 3-(4-(M-tolyl)piperazin-1-yl)propanoic acid (CAS 500294-64-4)
- 2-(2-Morpholinoethyl)-4-nitroisoindolin-1-one (CAS 900019-24-1)
- 5-(Hydroxymethyl)-4-(((2-(5-methoxy-1H-indol-3-yl)ethyl)imino)methyl)-2-methylpyridin-3-ol (CAS 98497-90-6)
- Lobophorin B DISCONTINUED (CAS 78798-30-8)
- tert-Butyl ((S)-1-((S)-2-aminopropanoyl)pyrrolidin-3-yl)carbamate (CAS 1401664-87-6)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com