Nimodipine EP Impurity A CAS 85677-93-6
| CAS No. | 85677-93-6 |
| Molecular Formula | C21H24N2O7 |
| Molecular Weight | 416.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Nimodipine EP Impurity A (CAS 85677-93-6) is a certified pharmaceutical impurity reference standard with the molecular formula C21H24N2O7 and a molecular weight of 416.42 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Nimodipine EP Impurity A is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 416.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H24N2O7 |
| Molecular Weight | 416.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Nimodipine Standards
- Nimodipine Impurity 20 (CAS CATO-C4X-138520)
- Nimodipine Impurity 29 (CAS CATO-C4X-138529)
- Nimodipine Impurity 30 (CAS CATO-C4X-138530)
- Nimodipine (CAS 66085-59-4)
- Nimodipine Impurity 18 (CAS CATO-C4X-138518)
- Nimodipine-d7 (CAS 1246815-36-0)
- Nimodipine Impurity 9 (CAS 116799-92-9)
- Nimodipine Impurity 25 (CAS 82219-47-4)
Recommended Standards
- N-Ethyl-2-(5-(hydroxymethyl)-2-((2-oxo-2-((4-(trifluoromethyl)phenyl)amino)ethyl)thio)-1H-imidazol-1-yl)acetamide (CAS 921866-14-0)
- Demeclocycline impurity 12 (CAS CATO-C4X-160812)
- 6-(Ethylthio)-1-phenyl-4-(3-(trifluoromethyl)phenoxy)-1H-pyrazolo[3,4-d]pyrimidine (CAS 478247-50-6)
- 2,4-bis(3,4-dimethoxyphenyl)cyclobutane-1,3-dicarboxylic acid (CAS CATO-C4X-22725)
- Paricalcitol Impurity 22 (CAS 1186587-44-9)
- Carbocisteine Impurity 30 (CAS CATO-C4X-201030)
- Minoxidil Impurity 37 (CAS 55034-35-0)
- 2-(2-Bromo-5-methylphenyl)acetic acid (CAS 203314-29-8)
- 3-(3-Bromo-5-methylthiophen-2-yl)-3-methylbutan-1-amine (CAS 1542556-57-9)
- 2-(4-Iodo-6-(trifluoromethyl)pyridin-2-yl)acetic acid (CAS 1393555-56-0)
- 1-(3-Methoxy-benzyl)-piperazine hydrochloride (CAS 1158445-27-2)
- 5-(2,2-Bis(ethylthio)ethyl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 338394-36-8)
- 3-Bromo-2-methyl-4-(4-(trifluoromethyl)benzyl)-4H-thieno[3,2-b]pyrrole (CAS 1207954-45-7)
- (Des-His1,Glu?)-Glucagon (1-29) amide (human, rat, porcine) (CAS 110084-95-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com