Nimodipine Impurity 25 CAS 82219-47-4
| CAS No. | 82219-47-4 |
| Molecular Formula | C20H24N2O7 |
| Molecular Weight | 404.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nimodipine Impurity 25 (CAS 82219-47-4, C20H24N2O7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Nimodipine Impurity 25 (C20H24N2O7) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Nimodipine Impurity 25 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O7 |
| Molecular Weight | 404.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 2 |
Related Nimodipine Standards
- Nimodipine Impurity 33 (CAS 39562-75-9)
- Nimodipine Impurity 9 (CAS 116799-92-9)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510-SS)
- Nimodipine Impurity 12 (CAS CATO-C4X-138512)
- Nimodipine EP Impurity B (CAS 21881-78-7)
- Nimodipine impurity 22 (CAS CATO-C4X-138522)
- Nimodipine Impurity 7 (CAS 82219-48-5)
Recommended Standards
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
- Linezolid Impurity 91 (CAS CATO-C4X-107391)
- Oseltamivir Impurity 112 (CAS CATO-C4X-1720112)
- Pinostilbenoside (CAS 58762-96-2)
- Alectinib Impurity 63 (CAS CATO-C4X-283663)
- Ramipril EP Impurity N (CAS 129939-63-5)
- Upadacitinib Impurity 5 (CAS CATO-C4X-24055)
- Methyl 2-acetyl-6-aminobenzoate (CAS 179678-23-0)
- 1-(4-Chloro-3-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 1520692-60-7)
- 3-Bromo-2-methyl-1-tosyl-1H-indole (CAS 1060812-81-8)
- 1,3-Dihydroxyacridine-9-carboxylic acid (CAS 28332-99-2)
- (1-(1-Methylpiperidin-4-yl)-1h-1,2,3-triazol-4-yl)methanamine (CAS 1437432-66-0)
- 2-Amino-6-chlorobenzimidazole (CAS 5418-93-9)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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