Biotin Impurity 33 CAS 863203-60-5
| CAS No. | 863203-60-5 |
| Molecular Formula | C24H28N2O4S |
| Molecular Weight | 440.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Biotin Impurity 33 (CAS 863203-60-5, C24H28N2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Biotin Impurity 33 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Biotin Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H28N2O4S |
| Molecular Weight | 440.56 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Biotin Standards
Recommended Standards
- N-(4-((4-(1H-Benzo[d]imidazol-2-yl)piperidin-1-yl)sulfonyl)phenyl)pentanamide (CAS 886904-95-6)
- H-Arg(Pmc)-OH (CAS 112160-37-9)
- H-Met-Tyr-Lys-OH (H-4375.0050) (CAS 73674-95-0)
- H-D-Arg(Pmc)-OH (CAS 191869-60-0)
- Brexpiprazole impurity 104 (CAS CATO-C4X-1131104)
- Bromfenac Impurity 37 (CAS CATO-C4X-200237)
- Elobixibat Impurity 30 (CAS CATO-C4X-283830)
- Sodium 3-hydroxy-5H-benzo[b]carbazole-2-carboxylate (CAS 116353-24-3)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethyl 2-propenoate and .alpha.-(2-methyl-1-oxo-2-propen-1-yl)-.omega.-hydroxypoly[oxy(methyl-1,2-ethanediyl)] (CAS 68298-93-1)
- 2-(2-(2-(Aminooxy)ethoxy)ethoxy)ethan-1-ol (CAS 313390-53-3)
- 3-Methoxy-2-pentenoic Acid Methyl Ester (CAS 104065-67-0)
- (1-(Ethoxymethyl)cyclopropyl)methanamine (CAS 1134331-34-2)
- 2-Amino-4-(aminooxy)butanoic acid (CAS 15985-61-2)
- Semaglutide impurity 208 (CAS CATO-C4X-2226208)
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