4-Bromo-5-nitrothiophene-2-carboxylic acid CAS 864075-31-0
| CAS No. | 864075-31-0 |
| Molecular Formula | C5H2BrNO4S |
| Molecular Weight | 252.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Bromo-5-nitrothiophene-2-carboxylic acid (CAS 864075-31-0), molecular formula C5H2BrNO4S and molecular weight 252.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-5-nitrothiophene-2-carboxylic acid (C5H2BrNO4S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Bromo-5-nitrothiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H2BrNO4S |
| Molecular Weight | 252.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 5-Bromo-3-nitro-thiophene-2-carboxylic Acid (CAS 101079-64-5)
- 5-Bromo-4-nitrothiophene-2-carboxylic acid (CAS 89283-24-9)
- 4-Bromo-1-(3-fluoropropyl)-2-nitro-1H-imidazole 472962-95-1 (CAS 472962-95-1)
- 4-Bromo-5-nitrophthalonitrile (CAS 206268-72-6)
- 2-Bromo-7-nitronaphthalene (CAS 102153-46-8)
- 3-Bromo-1-nitronaphthalene (CAS 102153-47-9)
- 6-Bromo-1-nitronaphthalene (CAS 102153-48-0)
- 7-Bromo-1-nitronaphthalene (CAS 102153-49-1)
Recommended Standards
- 3,5-Dimethoxybenzylzinc chloride (CAS 352530-33-7)
- 3,4-Dimethoxybenzylzinc chloride 0.5 M in Tetrahydrofuran (CAS 307531-79-9)
- 2,5-Dimethoxybenzylzinc chloride 0.5 M in Tetrahydrofuran (CAS 352530-32-6)
- 1-(Phenylsulfonyl)-1h-pyrazol-4-ylboronic acid (CAS 1201643-89-1)
- 2-(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)ethan-1-amine dihydrochloride (CAS 1332528-50-3)
- Ethyl 5,8-dimethoxy-4-(methylamino)quinoline-3-carboxylate (CAS 1215623-47-4)
- 3-[(E)-2-[(4-Methoxyphenyl)methylidene]hydrazin-1-yl]-1,2-dihydroquinoxalin-2-one (CAS 129227-25-4)
- 3-(Piperidin-1-yl)cyclobutan-1-amine, mixture of diastereomers (CAS 878155-05-6)
- 2-Bromo-6-(difluoromethyl)-5-formylnicotinonitrile (CAS 1805430-55-0)
- 2-Cyano-N'-[(1E)-4,4,4-trifluoro-3-oxo-1-phenylbutylidene]acetohydrazide (CAS 477862-81-0)
- 2-Isopropyl-N-(3-methylbenzyl)aniline (CAS 1039821-59-4)
- 3-(Difluoro(4-methoxyphenyl)methyl)bicyclo[1.1.1]Pentane-1-carboxylic acid (CAS 2198774-69-3)
- Bendamustine Impurity 10 (CAS CATO-C4X-127110)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com