Minocycline EP Impurity E CAS 864073-42-7
| CAS No. | 864073-42-7 |
| Molecular Formula | C23H28N4O6 |
| Molecular Weight | 456.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Minocycline EP Impurity E (C23H28N4O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Minocycline EP Impurity E (CAS 864073-42-7), a pharmacopoeial impurity reference standard (molecular formula C23H28N4O6, MW 456.49 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Minocycline EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H28N4O6 |
| Molecular Weight | 456.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related Minocycline Standards
- Minocycline Impurity 14 (CAS CATO-C4X-169914)
- Minocycline Impurity 50 (CAS CATO-C4X-169950)
- Minocycline Impurity N1 (CAS 10118-89-5)
- Minocycline EP Impurity A (HCl salt) (CAS 179471-96-6)
- Minocycline Amino Ethyl Derivative (CAS 4756-93-8)
- Minocycline Impurity (CAS 27179-27-7)
- Minocycline EP Impurity A (CAS 43168-51-0)
- Minocycline (CAS 10118-90-8)
Recommended Standards
- Cefpodoxime Impurity 56 (CAS CATO-C4X-157956)
- Cefuroxime Impurity 88 (CAS CATO-C4X-124588)
- Eltrombopag Impurity 24 (CAS 1437383-35-1)
- Pranlukast Impurity 1 (CAS 136450-10-7)
- Sofosbuvir Impurity 16 (CAS CATO-C4X-105216)
- Ivabradine Impurity 35 (CAS CATO-C4X-111935)
- Canagliflozin Impurity 98 (CAS CATO-C4X-112398)
- 4-(3-Ethoxy-2-methoxyphenyl)but-3-en-2-one (CAS 1286356-39-5)
- Salbutamol EP Impurity F(Trifluoroacetic Acid) (CAS CATO-C4X-117650)
- N-(4-Aminophenyl)-2-phenoxyacetamide (CAS 293327-23-8)
- Mivacurium chloride Impurity 40 (CAS CATO-C4X-137540)
- Ethyl (2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)carbamate (CAS 321432-03-5)
- 1-(4-Aminopiperidin-1-yl)propan-2-one (CAS 1251377-78-2)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com