N-Demethyldeacetyl Diltiazem CAS 86408-44-8
| CAS No. | 86408-44-8 |
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-Demethyldeacetyl Diltiazem is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-Demethyldeacetyl Diltiazem (CAS 86408-44-8), molecular formula C19H22N2O3S and molecular weight 358.45 g/mol, is a CATO reference standard with documented purity and traceability.
N-Demethyldeacetyl Diltiazem (C19H22N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Recommended Standards
- Butyl 4-({[(4-aminophenyl)thio]acetyl}amino)-benzoate (CAS 913247-25-3)
- Diltiazem Impurity 7 (CAS 84903-82-2)
- 3-Benzyl-7-(phenylsulfonyl)-9-oxa-3,7-diazabicyclo[3.3.1]nonane (CAS 335620-96-7)
- Ethyl 4-(cyclohexylsulfanyl)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 339031-39-9)
- Tert-butyl 6,7-dioxo-octahydro-1h-pyrazino[1,2-a]piperazine-2-carboxylate (CAS 1384699-68-6)
- Ethyl (2-methyltetrahydrofuran-2-yl)carbamate (CAS 61807-48-5)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5-(4-fluorophenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 764689-91-0)
- Propan-2-one O-((6-chloropyridin-3-yl)methyl) oxime (CAS 307929-00-6)
- N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide HCl (CAS 79127-24-5)
- 9-(1-hydroxyethyl)-7-methyl-2-morpholino-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1173900-35-0)
- 2-((5-(((4-Chlorophenyl)amino)methyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide (CAS 333314-33-3)
- Doxorubicin Impurity 31 (CAS CATO-C4X-203331)
- 5-Amino-1-ethyl-3-propylpyrimidine-2,4(1h,3h)-dione (CAS 1343709-76-1)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com